Tilapia skin showed good results when used as a biological graft for surgical management of Mayer–Rokitansky–Küster–Hauser syndrome. Thus, our researchers considered the use of this biomaterial for neovaginoplasty in radiation-induced vaginal stenosis. We report the case of a 41-year-old female patient with a total occlusion of the vaginal canal after radiotherapy for vaginal cancer. McIndoe neovaginoplasty using tilapia skin as a scaffold for proliferation of new vaginal epithelium was performed. Initially, laparoscopic dissection of the rectovaginal septum and vesicovaginal space spaces was conducted. In the vaginal surgical time, a transverse transmural incision was made in the scarred vaginal reminiscent followed by blunt dissection and insertion of an acrylic mold covered with tilapia skin. Good anatomical and functional outcomes were noted. Vaginal reconstruction with tilapia skin seems to be an excellent option for patients with radiation-induced vaginal stenosis due to its wide availability, easy application and high effectiveness.
Conclusion(s):The procedure described offered this patient an anatomic and functional neovagina by means of a simple, safe, easy, effective, quick, and minimally invasive procedure. Limitations include the experimental nature of this study, based on a single case report with no long-term outcome results. The tilapia fish skin is a lowcost and widely available biomaterial. (Fertil Steril Ò 2019;112:174-6. Ó2019 by American Society for Reproductive Medicine.) El resumen está disponible en Español al final del artículo.
Vaginal agenesis is a rare mal-formation of the lower female genital tract, with a prevalence of 1 in 5000 female newborns. Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome represents 90% of all causes and is caused by partial or complete aplasia of patients with 46 XX karyotype, functioning ovaries and normal external genitalia.
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