Objective: To evaluate vitamin D serum levels of term newborns and relate them to maternal concentrations and birth weight. Methods: Cross-sectional study carried out with 225 mothers and their term newborns. Data collected were maternal health, prenatal care, gestational, and anthropometric data of the newborns. The following laboratory tests were performed: serum levels of 25(OH)D, calcium, phosphorus, magnesium, and alkaline phosphatase. Results: Of the 225 newborns included in the study, 119 (52.9%) were males, the mean birth weight was 3,198 ± 421.4 g, and the gestational age was 39.1 ± 1.1 weeks. Of these, 20 (8.9%) were small and 12 (5.3%) were large for gestational age. A 25(OH)D sufficiency was found in 25.8% of mothers and 92% of newborns. The mean 25(OH)D concentrations of newborns was higher than that of the mothers 48.7 ± 15.2 ng/mL vs. 26.0 ± 6.7 ng/dL (p < 0.001), correlating inversely with birth weight (r = –0.249; p < 0.001). Small for gestational age (SGA) newborns had higher concentrations of 25(OH)D compared to adequate and large for age (p < 0.001). Conclusion: In conclusion, this study showed strong positive correlation between maternal and neonatal 25(OH)D concentrations, with higher values in newborns. The highest 25(OH)D concentrations were found in SGA term infants. We speculated these findings could be influenced by newborn body composition.
Objective To evaluate postpartum vitamin D deficiency/insufficiency and to relate it to pregestational BMI, gestational weight gain, and sociodemographic variables. Methods This is a cross-sectional study with 225 full-term pregnant women. Data collected are as follows: maternal health, socioeconomic status, pregestational body mass index (BMI), and gestational weight gain. Laboratory evaluation included vitamin D [25(OH)D], calcium, phosphorus, magnesium, and alkaline phosphatase. Results The mean age of women was 25.6±6.6 years. Dark skin color, low education, and work in the urban region were predominant. Regular sun exposure, photoprotection, and vitamin D supplementation were reported by 144 (64.0%), 44 (19.6%), and 5 (2.2%) women, respectively. The mean plasma concentrations of 25(OH)D were 26.0±6.8 ng/mL. Levels compatible with deficiency (<20 ng/mL) and insufficiency (20-30 ng/mL) were observed in 43 (19.1%) and 124 (55.1%) women, respectively. The increase of 1 ng/mL in 25(OH)D concentrations was associated with an increase of 0.16 mg/dL (95%CI 0.19 to 2.02; p=0.018) for calcium. There were no associations with 25(OH)D concentrations with pregestational BMI and with gestational weight gain. Conclusions The high frequency of postpartum vitamin D deficiency/insufficiency in women with a full-term pregnancy in a region with a large and permanent sun exposure reminds us of the need for intervention policies aimed at preventing vitamin D deficiency during pregnancy.
Resumo: O presente artigo objetiva refletir aspectos relacionados a Síndrome da Morte Súbita Infantil (SMSI). A SMSI é uma expressão usada para se referir a uma morte repentina e inesperada, na maioria dos casos inexplicável, que pode acometer os bebês no seu primeiro ano de vida. Trata-se de uma das maiores causas de morte infantil, ocupando inclusive a oitava posição nos países desenvolvidos. Em países como o Brasil, não existe uma coleta de dados que seja suficiente para uma avaliação das influências socioculturais ou geográficas quanto ao desenvolvimento da enfermidade. Ações educativas direcionadas às gestantes, mães, pais e cuidadores, podem ajudar a reduzir os casos de mortalidade subida infantil.
Palavras-Chave: Morte súbita. Mortalidade infantil. Políticas públicas.
Sudden Infant Death Syndrome (SIDS): Issues regarding the main causes and Prevention.Abstract: This article aims to reflect aspects related to Sudden Infant Death Syndrome (SIDS). SIDS is an expression used to refer to a sudden and unexpected death, in most cases unexplained, that can affect infants in their first year of life. It is one of the major causes of child deaths, occupying the eighth position in developed countries. In countries like Brazil, there is no data collection that is sufficient for an evaluation of sociocultural or geographic influences regarding the development of the disease. Educational actions aimed at pregnant women, mothers, fathers and caregivers can help reduce cases of infant mortality.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.