Group B streptococcus (GBS) is the leading etiologic agent of bacterial meningitis and sepsis during the neonatal period, but it is an infrequent cause of meningitis in adults. We report 12 episodes of group B streptococcal meningitis in adults and review 52 cases reported in the literature. A total of 24 men and 40 women were included in the study; the mean age ({ SD) was 49.2 { 20.5 years (range, 17 -89 years). All the patients had cerebrospinal fluid cultures positive for GBS. Eighty-six percent of the patients had comorbid conditions, 50% had a distant focus of infection, and blood cultures yielded GBS for 78.7%. The overall case-fatality rate was 34.4% (22 patients). Factors associated with a poor outcome were advanced mean age ({ SD) (61.5 { 17.4 years vs. 42.8 { 19.2 years; P Å .0003) and the presence of complications on admission (P Å .0001). Seven percent of survivors had neurological sequelae. Group B streptococcal meningitis in adults has become increasingly frequent in recent years; it tends to occur in patients with severe underlying conditions and is associated with a high casefatality rate. Factors associated with a poor prognosis are advanced age and the occurrence of neurological and extraneurological complications.

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Finally, it has been demonstrated that this procedure is simple, inexpensive, and avoids surgical intervention.

We treated a 28-year-old woman who had metachromatic leukodystrophy with bone marrow transplantation. Leukocyte arylsulfatase A levels increased to the donor's range after successful graft. Motor and sensory nerve conduction values did not change significantly in the 4 years after the transplant, and subcortical white matter lesions, as shown on MRI, remained stable during that period of time. The results, after 4 years of follow-up, indicate that the disease has not progressed and signs and symptoms are stabilized.

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E. coli is the most frequent causal microorganism in neonatal urinary tract infection. However, an association between the isolation of a microorganism of the Enterobacteriaceae family different to E. coli with the presence of vesicoureteral reflux and mainly with higher grades of vesicoureteral reflux exists.

RATIONALE: Rhintics allergyis a risk factor for the development of asthma, affects the quality of life, school, or work performance and impacts the family economy. This work was carried out to determine the behavior of rhintics allergy according to age and sex, sensitivity to allergy tests and the association with other allergic diseases. METHODS: A cross-sectional observational study that included patients attending the allergy clinic with symptoms of rhinitis (34.18% male and 65.81% female, mean age 31-45 years). In all cases, allergic clinical history and skin prick tests were performed. For demographic data, concomitant diseases and allergic symptoms, frequency tables were used for nominal variables. RESULTS: Of 1528 patients who were seen at the allergy clinic, 313 patients had rhintics allergy for 20.48%. The skin tests showed a greater sensitivity to the Dermatophagoides pteronyssinus with 42.49% in relation to the rest of the aeroallergens. 19.82% were associated with asthma, 12.10% with bronchial hyperreactivity. CONCLUSIONS: 20.48% of patients suffer from Allergic Rhinitis. Higher incidence in children under 15 years of age in males. Patients are more sensitive to the mite Dermatophagoides Pteronisino. Of the patients with allergic rhinitis 60% are associated with allergic conjunctivitis and 30% with bronchial asthma 403 Comparison of sensitization to prevalent pollens in two different ethnic populations of childrenadolescents born in the same region

Neonatal acute suppurative submandibular sialadenitis is an uncommon infection that presents similar clinical features through the years. As microbiological feature, this infection is usually caused by Staphylococcus aureus, although some methicillin-resistant Staphylococcus aureus have been implicated during the last 16 years. In general, it presents a satisfactory evolution with an early and appropriate antibiotic treatment.