Acrylate monomers have a wide range of applications. Since the 1950s, many reports of occupational origin allergic contact dermatitis due to (meth)acrylate monomers have been published. During last decades, (meth)acrylate allergy has undergone an occupational shift from dentistry toward beauty industry and medical devices. The aim of the study was to conduct a literature review on acrylates as a cause of allergic contact dermatitis, current sources of exposure as well as identification of professional groups with an increased risk of this allergy and methods of effective prevention. Database review: Medline search (PubMed), Wiley Online Library and Web of Science base in years 1956–2019 using the following keywords: acrylates, manicurists, dentists, dental technicians, medical devices, occupational exposure, and allergic contact dermatitis. 204 346 articles containing the term ‘acrylates‘ have been found. They include 2 042 articles with the word ‘manicurists’, 169 919 – ‘dentists’, 218 236 – ‘dental technicians’, 2 427 418 – ‘medical devices’. Fifty-nine articles were chosen based on analysis of abstracts and full texts. In the past allergy to acrylates was mainly of occupational origin and dental technicians were the most often affected professional group. Since the long-lasting manicure has become popular, this problem concerns both manicurists and their customers. Moreover, the new significant trend is non-occupational allergic contact dermatitis caused by medical devices especially dedicated to diabetes patients.
Introduction: In the last decades the number of skin carcinomas has dramatically increased, which is mainly connected with changes in lifestyle, especially with common use of artificial light sources such as sunbeds. Basal cell carcinoma (BCC) is the most common form of skin cancer in white populations. Basal cell carcinomas are divided into subtypes, depending on their clinical picture and histology. The main groups are nodular (nBCC) and superficial (sBCC) ones. The major recognized risk factors for basal cell carcinoma (BCC) are exposure to chronic and intermittent burning doses of sunlight. Other risk factors leading to the development of the nBCC and sBCC subtypes of BCC are not well established. Material and methods: An analysis of 123 patients with either nBCC or sBCC, living in Lodz, Poland, regarding various intrinsic and environmental parameters was undertaken following the histological diagnosis of BCC. Results: No statistical differences were observed between the BCC subtype and sex, age, hair colour, eye colour, smoking, family history of skin cancer, occupation, or past episodes of sunburn. While sBCCs tended to occur on unexposed body sites in phototype I/II subjects who mainly avoided direct sunlight, nBCCs tended to occur on sun-exposed body sites in phototype III subjects who were frequently in direct sunlight. Conclusions: Thus the development of particular BCC subtypes is partially dependent on phototype and personal sun behaviour.
Suberythemal UVB radiation was sufficient to cause changes in the expression of several epidermal cell cycle proteins. When tested by irradiation with a single erythemal UVB dose following the repeated exposures, no photoprotection against the UV-induced alteration in cell cycle protein expression was apparent.
Larval therapy in recent years has gained more interest as a method of treating chronic wounds. It could be an alternative to conventional therapies due to the increasing multidrug resistance of bacteria and observed allergic reactions to antibiotics and disinfectants. The aim of the study was to evaluate the effectiveness and safety of the treatment on the basis of a review of medical databases. Results of the studies have demonstrated greater maggot debridement therapy (MDT) effectiveness in the debridement and stimulation of granulation process over conventional methods. In addition, using this method can shorten the healing time, reduce the consumption of antibiotics, and reduce the cost of treatment. The results of analysed studies are promising; however, it would be advisable to perform randomised, blinded studies with longer follow-up time, in which a larger group of patients would participate. Streszczenie Larwaterapia w ostatnich latach zyskuje coraz większe zainteresowanie jako metoda leczenia ran przewlekłych. Stanowi alternatywę dla konwencjonalnych metod terapii ze względu na rosnącą wielolekooporność bakterii i obserwowane reakcje alergiczne na antybiotyki i środki odkażające. Celem pracy była ocena skuteczności i bezpieczeństwa larwaterapii na podstawie przeglądu medycznych baz danych. Wyniki badań wskazują na większą skuteczność larwaterapii w oczyszczaniu ran z martwej tkanki oraz pobudzaniu procesu ziarninowania w stosunku do metod konwencjonalnych. Zastosowanie larwaterapii umożliwia skrócenie czasu leczenia, ograniczenie zużycia antybiotyków i zmniejszenie kosztów leczenia. Wyniki analizowanych badań są obiecujące, natomiast wskazane byłoby zaplanowanie badań z randomizacją przeprowadzonych metodą podwójnie ślepiej próby, z dłuższym czasem obserwacji, w których uczestniczyłaby większa liczba pacjentów.
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