COVID-19 (corona virus disease 2019) is a global public health emergency caused by a new corona virus with severe acute respiratory syndromelike characteristics (SARS-CoV-2). We aimed to evaluate whether gender and age are major risk factors for SARS-CoV-2 infection. For the study,
300 positive cases diagnosed during the period of July 2020 to September 2020 were included. Results showed that 69% of study samples were
male of which 84% were in the >51 years old age group. And 31% of study samples were female of which 63% were in the 4-19 years old age group.
ANOVAresults indicated that the means of Ct values varied signicantly between age groups (F=2.703; p-value= 0.045). The lower Ct values were
recorded in males (29.01±4.35) in comparison to females (29.84±3.98) while, the difference between the means of the two groups was not
signicant. Our study concluded that males have higher viral load than females and for both sexes, age was found to be a signicant risk factor for
severity of COVID-19.
Background: The ongoing novel coronavirus (COVID-19) pandemic is shaping the world on an unprecedented scale affecting more than 10.3 million individuals across the globe . Various studies have found that C- reactive protein (CRP ) levels could reflect disease severity and should be used as a key indicator for disease monitoring .
Objective:
To assess the level of C reactive protein(CRP) in initial stage of COVID-19 cases and its correla-tion with clinical presentation of disease.
Materials and method:This retrospective case-control study includes 60 RT- PCR (reverse tran-scriptase-polymerase chain reaction) confirmed positive cases above the age of 18 years who were subsequently admitted between May- June, 2020, at Mahendra Mohan Choudhury Hospi-tal(MMCH) –an annexe hospital of Gauhati Medical College and Hospital(GMCH), Kamrup, As-sam.
Result:The mean CRP value in the case group was 6 ± 2.36 mg/L while in control group it was 3.03 ± 1.20 which was found to be significantly raised (p<0.005)
Conclusion: CRP may be an important index for prognosis and assessment of early stage of COVID-19. CRP levels can also be used in the treatment and management of positive cases.
Background And Objectives : Scrub typhus is a chigger-borne zoonotic disease, caused by Orientia tsutsugamushi. Humans are accidental hosts. It occurs all along East Asia with many recent outbreaks in North-East India. It shows similar symptoms to other tropical infections and its disease spectrum ranges from mild febrile illness to severe life-threatening illness with multi organ dysfunctions. This study was done to observe relationship between scrub typhus and liver function. Methods : A hospital based observational study was conducted on randomly selected 40 scrub typhus patients ( between 12 and 60 years) diagnosed by detecting IgM antibody using enzyme linked immunosorbent assay (ELISA) over a period of 1 year at a tertiary care centre, Assam. Liver function tests were performed on the diagnosed cases using reectance spectrophotometry method on automated analyser. The values of LFT were estimated and p-values were calculated to establish statistical signicance. Results : Total 40 number of cases of scrub typhus was taken for our study with a mean age of 29.28 years among which, males were 57.5% and females were 42.5%. Bilirubin elevation was seen in 25 patients (62.5%), AST was increased in 36 patients (90%), ALT was increased in 35 patients (87.5%), ALK was high in 25patients (62.5%), 32 pateints (80%) had hypoalbuminemia, with a p value of < 0.05, which is statistically signicant. Interpretation And Conclusion : Our study concluded that scrub typhus could to be taken into consideration in patients with undifferentiated fever with abnormal liver function tests.
A 7 year old boy with a history of repaired tetralogy of Fallot with aortic valve replacement was scheduled to undergo laparoscopic cholecystectomy. His significant history comprises of post cardiac surgery with warfarin anticoagulant. Perioperatively warfarin was converted to low molecular weight heparin and the patient underwent general endotracheal anaesthesia with caudal epidural anaesthesia for laparoscopic cholecystectomy. Anaesthesia induction, intraoperative course and postoperative period proceeded uneventfully and the patient quickly progressed to the preoperative level of functioning. The perioperative anticoagulant management in such patients of repaired tetralogy of Fallot with aortic valve replacement is reviewed.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.