SUMMARYIn the present paper the main aspects of the natural history of human infection by Toxocara larvae that occasionally result in the occurrence of visceral and/or ocular larva migrans syndrome were reviewed. The contribution by Brazilian researchers was emphasized, especially the staff of the Tropical Medicine Institute of São Paulo (IMT).
The aim of this note was to record for the first time the recovery of Toxocara canis larvae from tissues and organs of Rattus norvegicus (Berkenhout, 1769), Wistar strain, until the 60th day after experimental infection. Rats were orally infected with embryonated T. canis eggs, killed on days 3, 5, 8, 10, 15, 30, and 60
SUMMARYUsing an elevated plus maze apparatus and an activity cage, behavioral changes in Rattus norvegicus concomitantly infected by Toxocara canis and Toxoplasma gondii were studied, during a period of 120 days. Rats infected by Toxocara canis or Toxoplasma gondii showed significant behavioral changes; however, in the group coinfected by both parasites a behavioral pattern similar to that found in the group not infected was observed thirty days after infection, suggesting the occurrence of modulation in the behavioral response.
SUMMARYSoil contamination by embryonic eggs of Toxocara canis is the main source of human infection by this ascarid larvae resulting, sometimes, in the occurrence of visceral larva migrans syndrome. The objective of the present research is to determine the frequency of T. canis eggs in soil samples monthly collected in nine public places, located at the South Region of São Paulo municipality in a 18-month period, from February 2004 to July 2005. The soil samples collected were treated with a 30% antiformine solution and with a sodium dichromate solution (d = 1.40) and microscopic slides were prepared and examined under light microscopy for searching T. canis eggs. Two peaks of higher frequency had been found, one in
La toxocariasis es actualmente considerada una importante zoonosis en muchos países y es generalmente atribuida a larvas de Toxocara canis (Werner, 1782, entretanto, a pesar de ser menos frecuente, T. cati (Schrank, 1788) puede causar enfermedad. El objetivo de este estudio fue comparar las rutas de migración seguidas por T. canis y T. cati en Rattus norvegicus (Berkenhout, 1769) y determinar el porcentaje de larvas obtenidas en cada órgano de las ratas infectadas experimentalmente. Veintiún especímenes machos de R. norvegicus (Wistar), con ocho semanas de edad fueron inoculados oralmente con 500 huevos larvados de T. canis, en cuanto que otras 21 ratas de la misma especie fueron inoculadas oralmente con 300 huevos embrionados de T. cati. En los días 3, 5, 8, 10, 15, 30 y 60 pos-infección, tres ratas de cada grupo fueron sacrificadas y la recuperación de larvas fue realizada en varios órganos y la musculatura después de la digestión con el método de HCl a 0,5%. La comparación de los porcentajes de larvas recuperadas reveló que las larvas de T. cati migraron para los pulmones en mayor cantidad, luego en el tercer día pos-infección (23,77%, y solamente 0,34% en el caso de T. canis) al paso que la migración de larvas de T. cati para la musculatura fue observada desde el día 3 hasta el día 60 pos-inoculación. Con este experimento se verificó que las larvas de estas dos especies siguen rutas de migración distintas y tienen tasas de recuperación diferentes.
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