Polycystic ovarian syndrome (PCOS) is caused by abnormal production of androgens resulting in the formation of small fluid-filled sacs in the ovaries. This condition worsens the life quality of women by disturbing their physiology and psychology in reproductive age. PCOS may also be associated with other morbidities like diabetes and hypertension. Numerous factors like imbalanced dietary patterns, poor lifestyle activities, improper care and medication, late diagnosis, and ignorance are involved in the prevalence of this disease in women. Hence, an early diagnosis and improved dietary and lifestyle management may improve the life quality and timely recovery of the patient from this disease. Various herbal extracts show a positive correlation in reducing the indicators associated with PCOS. This review discusses the effect of dietary and lifestyle practices on PCOS as prominent features. It has been recommended that a balanced diet with 40% energy from carbohydrates, 30% from fats, and 30% from protein with optimum physical activity could reduce severe PCOS symptoms and improve metabolic balance. Furthermore, recommendations for modification of diet and lifestyle activities are made which may positively influence the recovery from PCOS. Practical applicationsPolycystic ovarian syndrome (PCOS) severely affects the life quality of suffering women. The dietary patterns, lifestyle activities, and co-medical conditions collectively affect the severity and related consequences of PCOS. This article provides sufficient information on dietary and lifestyle modifications to effectively manage this disease. Furthermore, dietitians, nutritionists, gynecologists, and obstetrics physicians can benefit from the information provided in it to understand and develop the management strategies to alleviate the disease symptoms and severity.
Cellulases are inducible enzymes that are synthesized by many microorganisms during their growth on cellulosic materials. Production of cellulase enzyme from bacteria has gained interest for applications in industries owing to their stability, catalytic activity and ease of production. In current study, total 40 cellulolytic bacteria were screened by agar well diffusion assay followed by Congo red stain. Cellulolytic bacteria were evaluated for detergent compatibility and de-staining ability. Bacterial cellulase production was optimized at different environmental conditions. Biochemical testing was done following Bergey’s manual. Ten cellulolytic bacteria selected, were gram positive. Bacteria showed best cellulolytic activity at 40oC to 60oC, at pH 9, lactose as carbon source and peptone as nitrogen source. Best hydrolysis zone shown was 45mm from strain MS22 and least zone was 6mm. The maximum detergent activity for surf excel was observed for G2 while the lowest was observed for MW22. Similarly, maximum activity for ariel and bonus were observed for RS5 and C3. G1 and C3 showed better clearance of ink as compared to other strains. In de-staining, G1, C1and MW17 showed better clearance of edible oil and G1, C2 and MW18 showed better clearance of grease. These promising cellulolytic bacteria can be used for various applications in different industries.
Introduction: Diabetes mellitus is a huge global health issue, affecting more than 350 million people worldwide, and the number might rise to 439 million in 2030. Diabetes Mellitus is associated with many complications. Most of these complications usually develop after many years or even decades of exposure to chronic hyperglycemia. Diabetic Nephropathy is one of the most common and grave complication of diabetes mellitus and is associated with increased morbidity and mortality. Study Design: A cross-sectional study was performed on 285 patients from August 2021 to February 2022 on all newly diabetic patients in Hayatabad Medical Complex, Peshawar. Their 24-hour urine for protein analysis was measured to screen them for proteinuria.After measuring the urine protein level in each patient, the study's total frequency was computed across all the patients who had been diagnosed. Data was recorded into a proforma. Results: The age range in this study was from 15 to 70 years with a mean age of 43.01±6.90 years, mean BMI was 27.67±1.99 Kg/m2, and mean proteinuria levels were 42.38±34.142mg/ dl. Males constituted the majority of the patient-group (62.1%). 34.7% of patients were also hypertensive. Proteinuria was seen in 114 patients (40%). Conclusion: This study has concluded that screening for the complications of diabetic patients is beneficial in the preventive management of the disease. Keywords: Diabetic patients, proteinuria
Background: Major public health risk was ‘Dengue infection’ initial discovery is critical to improving the existence in serious infection of dengue. Our objective in this study was to investigate the serum ferritin level to suppose biomarker in the diagnosis of dengue fever. Method: An observational and prospective study was conducted in the Hayatabad Medical Complex and it included one hundred nineteen cases related to dengue was diagnosed by using NSI Test antigen or serology test related to specific dengue that internment “ELISA”. At the time of diagnosis, serum ferritin was measured. Monitoring the clinical and platelets counts was done on daily bases, it also classified into two groups such as non-severe and severe groups by allowing WHO criteria in 2009. Result: Five out of 119 cases of dengue were severe, dengue patients had lower platelets when they are in severe condition, count the number of platelets (p less than 0.0001); Ferritin level almost high (p=0.02) and the value of hospital longer time period (p less than 0.0001) mostly in severe group as compare to non-severe group of dengue. Platelets count had negative value with age factor almost Positive correlations with ferritin levels (p=0.08 or r= 0.16) and a longer hospital stay (r= -0.427 and p 0.0001) were also found (r= 0.26, p= 0.004). These values indicate the severe risk of dengue infection/ disease. Negative value of serum ferritin that are related to the value of platelets (r=0.51 and p< 0.001). On day 4 of clinical infections, an elevated value of ferritin is seen in severe cases. Conclusion: In Clinical practice, a biomarker for determining the severity of dengue infection is increased serum ferritin concentrations. Keywords: Biomarkers, Serum ferritin, Severity, Dengue infection, Predicators
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.