Background: Filariasis, a global problem, is a major public health issue in India. Despite its high incidence, it is unusual to detect microfilaria in cytological smears, though unexpected detection of microfilariae in fine needle aspiration cytology (FNAC), exfoliative and fluid cytology have been reported previously. The study analyzed the role of cytology in detection of asymptomatic carriers of microfilariae. Methods:This was a retrospective, observational study and included cases of filariasis from cytological records spanning five years. The epidemiological, clinical, hematologic and radiologic details were noted. The slides were retrieved and examined. Descriptive statistical analysis was utilized.Result: Filariasis was diagnosed in 0.03% of the total cytology cases studied during the period, constituting 0.04% of FNACs (two cases of inguino-scrotal swellings, two of breast lumps, one of thyroid swelling) and 0.02% of cervicovaginal smears (two cases). None of them was clinically suspected to be filariasis. Radiological examination was also misleading. None of the cases demonstrated raised leukocytosis or microfilaremia and eosinophilia was present in 3 cases (42.9%). Apart from microfilariae of Wuchereria bancrofti, eggs were present in one case. This was associated with inflammation in all cases, cell adherence in 42.9% and coexistent hyperplastic and neoplastic conditions in 57.1% cases. Conclusion:The detection of microfilariae in cytological material in the absence of clinical, radiologic or hematologic suspicion, in an area of relatively low prevalence of filaria, points to the need for a high index of suspicion and careful screening of all smears, as cytology may play an important role in the diagnosis of asymptomatic carriers of microfilariae.

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Nevus Lipomatosus Cutaneous Superficialis (NLCS) is an idiopathic, rare skin hamartoma. It occurs due to ectopic deposition of adipocytes in dermis. There are two main clinical forms of NLCS- classic and solitary. Both have different clinical presentations but histologically they show similar morphology characterised by bundles of mature adipocytes in the superficial and deep dermis separated by bundles of collagen. The hallmark of this lesion is absence of connection between subcutaneous fat and adipocyte clusters in dermis.Though NLCS is benign developmental disorder and remains static for a long time, it can be cosmetically unpleasant if grows to a large size. Herein, authors report a case of a 21-year-old male with a solitary painless pedunculated lump in right thigh for 10 years that clinically presented as giant lipoma due to its soft consistency, cut surface of the mass was yellow and fibrofatty. There was no connection of these adipocytes seen with the subcutaneous fat. Focal collections of adipocytes were also seen around the blood vessels. Sparse perivascular mononuclear inflammatory infiltrate also noted. Final diagnosis of NLCS was made.

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Introduction: COVID-19 infection can be complicated by coagulation derangement and a high risk of thromboembolic episodes. Our study aimed to investigate coagulation parameters in COVID-19 patients and their correlation with clinical severity. Methods: We analyzed coagulation parameters PT, APTT, D-Dimer, and Fibrinogen in 98 RT-PCR-confirmed COVID-19 patients admitted to the