Summary. In Schizosaccharomyces pombe the experiments performed in order to assess some possible influence of caffeine on biological processes related to the induced or spontaneous mutations and meiotic recombinations, have shown that caffeine decreases UV-and NGinduced forward mutations at ad-6 and ad-7 loci and UV-induced reverse-mutations of hismutants whereas spontaneous mutations to adenine or histidine independence were not affected; intergenic meiotic recombinations in the lVlT chromosomal region were also decreased when caffeine was present in the crossing medium.
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