Coagulation abnormalities have been reported in COVID-19 patients, which may lead to an increased risk of Pulmonary Embolism (PE). We aimed to describe the clinical characteristics and outcomes of COVID-19 patients diagnosed with PE during their hospital stay. We analyzed patients with PE and COVID-19 in a tertiary center in Mexico City from April to October of 2020. A total of 26 (100%) patients were diagnosed with Pulmonary Embolism and COVID-19. We observed that 14 (54%) patients were receiving either prophylactic or full anticoagulation therapy, before PE diagnosis. We found a significant difference in mortality between the group with less than 7 days (83%) and the group with more than 7 days (15%) in Intensive Care Unit ( P = .004); as well as a mean of 8 days for the mortality group compared with 20 days of hospitalization in the survivor group ( P = .003). In conclusion, there is an urgent need to review antithrombotic therapy in these patients in order to improve clinical outcomes and decrease hospital overload.
HighlightsCarotid body tumors (CBT) are rare neoplasms with malignant potential.The concomitant presentation of a CBT with goiter has been only reported in one case in 1950.The extended Kocher incision for resection of both tumors was performed succesfully.
Objectives Retroperitoneal tumor resection commonly disturbs major vessels; therefore, surgical teams can recruit vascular surgeons to prevent injuries and improve the prognosis of oncologic patients. The objective of the present study is to establish long-term survival after retroperitoneal tumor resection surgery with an emphasis on the potential impact of preventing or repairing major vessel injuries when tumors are adjacent to the aorta or vena cava. Methods Retrospective case series including all cases of surgical removal of retroperitoneal tumors between 2007 and 2020 in a highly specialized hospital in Mexico City. Long-term survival was defined as 5 years after surgical intervention. Descriptive statistics, group-comparison tests, and regression analysis were performed using Stata 16. Results From a total of 70 cases, vascular injury occurred in 30 (42.8%) and the vascular surgeon intervened in 19 (27.1%) of them, 4 (21%) were performed by a vascular surgeon with planned intervention, and in 9 (47.3%) cases the vascular surgeon was called to join the surgery due to emergency. Intraoperative bleeding was 2-fold greater in the group with an emergent participation of vascular surgery in contrast with the planned intervention group (4, 235 mL vs 2, 035 mL, p = 0.04). The regression model revealed a significant association between the intervention of a vascular surgeon and long-term survival (OR 59.3, p = 0.03) after adjusting for sociodemographic and characteristics of oncologic nature. Conclusions Planned intervention of vascular surgeons in retroperitoneal tumor resection may have a positive impact not only in trans-operatory period, but also on long-term survival.
Desde el inicio de la llamada pandemia por el síndrome respiratorio agudo severo por coronavirus 2 (SARS-CoV-2) se han publicado numerosos reportes de complicaciones tromboembólicas tanto venosas como arteriales en pacientes con enfermedad por coronavirus 2019 . Todavía no se conocen con exactitud los mecanismos a través de los cuales los pacientes desarrollan un estado de hipercoagulabilidad, inclusive con mayor frecuencia que pacientes en las unidades de cuidados intensivos con otro tipo de padecimientos. Una de las estrategias fundamentales para evitar complicaciones en estos pacientes es la profilaxis o tratamiento anticoagulante. El objetivo de este trabajo de investigación consiste en orientar en el tratamiento de la enfermedad tromboembólica venosa en pacientes con COVID-19 hospitalizados. El presente artículo presenta una revisión de los artículos más destacados con recomendaciones específicas tanto para la profilaxis como para el tratamiento de la enfermedad tromboembólica venosa en pacientes con COVID-19, tanto hospitalizados graves como no graves, duración del tratamiento y esquema de medicamentos al egreso hospitalario. Las estrategias de tratamiento para estas complicaciones son aún inciertas, y hasta que no se encuentre una estrategia efectiva para evitarlas, las recomendaciones internacionales son nuestra mejor opción.
In Latin America, 51 995 emergencies and 337 deaths are caused by snakebites yearly. Prompt and adequate treatment is crucial after an envenomation. We here report the case of a 40-year-old male agriculturalist, who was bitten by a venomous snake. Hours after the bite, he was admitted at the nearest clinic, diagnosed with type IV envenomation. After initial antivenom treatment he was transported to an urban hospital. Hemorrhage persisted and the patient developed compartmental syndrome and renal failure. The patient died 3 days after the accident. To reduce fatalities from snakebite envenomation, such as the case we here presented, there is a need for coordinated and multilevel approach, collaborative work and continual medical training.
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