A case report of a concomitant total thyroidectomy and carotid body tumor resection in a 43 year old female

Abstract

HighlightsCarotid body tumors (CBT) are rare neoplasms with malignant potential.The concomitant presentation of a CBT with goiter has been only reported in one case in 1950.The extended Kocher incision for resection of both tumors was performed succesfully.

Assessment of health-related quality of life in patients prior to carotid body tumor resection

“…1 Scores are expressed in a 0-100 scale in which a higher score indicates a better quality of life (QoL). 4 Even though CBTs are usually benign asymptomatic neoplasms, their proximity to cranial nerves as to the vasculature in the neck can result in signs and symptoms that are reported to cause a decrease in the HRQoL. 4,5,12,13,14 As aforementioned, surgical resection is a wellestablished treatment in these patients; however, assessment of HRQoL has become a subject of great importance when deciding which treatment could bring more benefit to the patients; given that the near absence of the pathology (i.e.…”

“…1 There has not been an established etiology to these tumors, nevertheless some risk factors have been associated to the enlargement of the carotid body is an increased response to chronic or intermittent exposure to hypoxia, 2 which could be caused by smoking, Chronic Obstructive Pulmonary Disease (COPD) or in those who live at high altitude locations such as metropolitan areas in central Mexico where our Institution is located. 1,3,4 Malignant CBTs have been reported in the literature, some of them being familial type CBTs, involving predominantly young patients with an autosomal dominant genetic pattern. While malignant CBTs are defined by the clinical behavior, these tumors have been reported to metastasize to cervical lymph nodes, lungs, bones, liver, breast, pancreas kidneys and brain.…”

“…While malignant CBTs are defined by the clinical behavior, these tumors have been reported to metastasize to cervical lymph nodes, lungs, bones, liver, breast, pancreas kidneys and brain. 4,5 Mutations in mitochondrial complex II subunits A, B, C and D of the succinate dehydrogenase (SDH) gene have been related with these tumors. [6][7][8] The most common subunit mutation related to malignant CBTs is the SDHB.…”

“…1 There has not been an established etiology to these tumors, nevertheless some risk factors have been associated to the enlargement of the carotid body is an increased response to chronic or intermittent exposure to hypoxia, 2 which could be caused by smoking, Chronic Obstructive Pulmonary Disease (COPD) or in those who live at high altitude locations such as metropolitan areas in central Mexico where our Institution is located. 1,3,4…”

Carotid Paragangliomas Related to Form Involving Multiple Systems (Syndromes and Diseases): A Systematic Literature Review

“…Autosomal dominant hereditary character. (thyroids and CPG) has been performed successfully on two occasions [22,24]; the resection of a CPG and a full thyroidectomy in the same successful surgical procedure has also been reported in situations involving a benign pathology of the thyroids [52]. Nevertheless, the decision to perform concomitant or sequential surgery on these patients should always be made on a case-bycase basis.…”