The objective of this study was to evaluate the metabolic profile, the activity of blood neutrophils, and the immunoglobulin G levels of primiparous and multiparous sheep (Lacaune breed) during the first 30 days after lambing. Fifteen primiparous ewes (GPR) and 15 multiparous ewes (GPM) were used. Evaluations were performed on the days of lambing and at three, seven, fifteen and thirty days post-lambing. In general, the basal and bactericidal activity of neutrophils were lower in GPR than in GPM. Phagocytosis was greater in the primiparous sheep in the initial moments after lambing. Non-esterified fatty acid concentrations were highest for GPM, indicating a negative energy balance in this group. The results obtained in this study allow us to conclude that primiparous sheep have higher neutrophil phagocytosis, while this cell type has higher bactericidal activity in multiparous sheep. Multiparous ewes presented with higher lipomobilization due to maintenance needs and higher milk production.
The objective was to evaluate the influence of clinical (HC) and subclinical (HSC) hypocalcemia on the energetic metabolism and innate immune response of cows. The samples were divided into groups: Group 1: 74 samples (control), Group 2: 142 samples (HSC) and Group 3: 6 samples (HC). There was no difference in BHB and immune response. In G2 higher values of AGNE were detected on the day of delivery. In G3 higher levels of AGNE were observed on the 15th day postpartum in relation to the 30th day. Higher values of glucose were detected in G3 compared to G1 and G2. Thus, hypocalcemia did not cause alterations in the immune response but altered the energetic metabolism during the transition period.
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