Dengue Hemorrhagic Fever (DHF) is a severe form of dengue fever (DF), which can be life threatening. The first recorded epidemic of dengue was reported in the late 18 th century and affected Asia, Africa, and North America. Female mosquitoes, predominantly of the species Aedes aegypti and less commonly, Aedes albopictus, are responsible for the transmission of the dengue virus. As the most dangerous and widespread mosquito-borne viral infection, the dengue virus affects more than 100 countries worldwide. Increasing 30-fold in the last 50 years, the social and economic effects of dengue are far reaching and of worldwide concern. The disease is widespread throughout the tropics with local variations in risk influenced by rainfall, temperature, and unplanned rapid urbanization. Upto 400 million people are infected each year. Currently, vaccines are still under development for DHF; therefore, prevention is of utmost importance in lessening the impact of dengue on a global scale. This review article summarizes the global epidemiology of Dengue Hemorrhagic fever by utilizing the most recent and available information on the topic.
Patient: Female, 36Final Diagnosis: Mediastinal cystic hygromaSymptoms: Chest discomfortMedication: —Clinical Procedure: —Specialty: PulmonologyObjective:Unusual clinical courseBackground:Lymphangioma is an atypical non-malignant, lymphatic lesion that is congenital in origin. Lymphangioma is most frequently observed in the head and neck, but can occur at any location in the body. About 65% of lymphangiomas are apparent at birth, while 80–90% are diagnosed by two years of age. Occurrence in adults is rare, as evidenced by less than 100 cases of adult lymphangiomas reported in the literature.Case report:A 36-year-old Indian woman with a medical history of recurrent pleural effusions presented with chief complaints of dyspnea on exertion for one year and a low-grade fever for one month. A thorax CT revealed left-sided pleural effusion with thin internal septations. Thoracoscopy revealed a large cystic lesion arising from the mediastinum from the hilum surrounding the mediastinal great vessels. The diagnosis of lymphangioma was confirmed via histopathologic examination of the cyst. It was managed with partial cystectomy along with the use of a sclerosing agent (talc).Conclusions:The size and location of lymphangiomas can vary, with some patients presenting with serious problems like respiratory distress, while others may be asymptomatic. Complete cyst resection is the gold standard treatment for mediastinal cystic lymphangioma. Partial cyst resection along with the use of sclerosing agents can be an effective option when complete cystectomy is not possible. Although lymphangioma is a rare patient condition, it should be included in the differentials for patients presenting with pleural effusions. Also, a biopsy should be done at the earliest opportunity to differentiate lymphangioma from other mediastinal malignant tumors.
Plasmodium falciparum can cause severe infection and has the shortest incubation period compared with all the other Plasmodium species. Incubation periods of 9–14 days for the immune and 6–14 days for the nonimmune have been reported for P. falciparum. However, an incubation period of less than 5 days has not been reported, as of yet. This report presents a case of a 23-year-old nonimmune female who presented with signs and symptoms 4 days after being bitten by mosquitoes while visiting Ghana. The patient was successfully treated with a 1-day course of parenteral artesunate, followed by a 3-day course of oral artemisinin combination therapy.
This study was carried out on the Caribbean Island of Anguilla for the purpose of analyzing surveillance data related to the epidemiology of HIV infection in Anguilla from 1988 to 2011. We retrieved data from the National AIDS Programme office for research purpose. Data on HIV/AIDS in Anguilla were retrieved from 1988 to 2011 and analyzed with particular emphasis on the year 2011. The retrieved data provided key information on new cases, deaths, and treatment of existing cases. Result analysis shows that by December 31, 2011, the cumulative number of all HIV cases diagnosed since the surveillance started in 1988 was 42. Males accounted for 23 (54.8%), while females accounted for 19 (45.2%) of the diagnosed cases. There were 17 cases comprising 12 males (70.5%) and 5 females (29.5%), HIV-related deaths within the same period. No cases of AIDS were reported in the study period. The year with the highest number of HIV diagnosis was 1996, with 7 confirmed new cases. HIV prevalence in Anguilla is estimated to be 0.19%. The number of tests conducted in 2008 holds steadfast as the highest in the 4 consecutive years from 2008 to 2011. There were 9 clients that received treatment and care from the Clinical Care Coordinator within the period under review. Data provided in this study shows a gradual decline in the incidence of HIV infection in Anguilla since it was first diagnosed in 1988. This is attributable to public awareness, surveillance, and access to antiretroviral treatment (ARVT).
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