Anemia merupakan salah satu masalah yang banyak dialami anak dengan penyakit ginjal kronik. Banyak faktor yang berperan dalam timbulnya anemia pada penyakit ginjal kronik. Dampak anemia pada anak dengan penyakit ginjal kronik adalah menurunnya kualitas hidup, gangguan fungsi organ, dan meningkatnya mortalitas. Ada beberapa modalitas tata laksana anemia pada anak penyakit ginjal kronik. Anemia is the most common problem in children with chronic kidney disease. Many factors contribute for anemia risk in chronic kidney disease. The impact of anemia on children with chronic kidney disease are decreased quality of life, impaired organ function, and increased mortality. There are several modalities for the management of anemia in children with chronic kidney disease.
Establishing reference ranges of the complete blood count (CBC), reticulocyte hemoglobin content (Ret-He), immature reticulocyte fraction (IRF), and reticulocyte production index (RPI) helps diagnose a disease related to the changes in erythrocyte indices, white blood count, platelets, and reticulocytes, especially in babies. Therefore, the study aims to establish a reference range for CBC and reticulocyte parameters in healthy babies aged 1–4 months. The study design was a cross-sectional study with descriptive analysis of CBC and reticulocyte in babies aged 1–4 months. Three hundred forty-eight babies met the inclusion criteria. This study recruited 89 babies aged 1 month, 87 babies aged 2 months, 86 babies aged 3 months, and 86 babies aged 4 months. The P5-P95 reference range of healthy babies for hemoglobin (Hb) aged 1 month, 2 months, 3 months, and 4 months was 9.95 to 15.45 g/dL, 9.74 to 13.42 g/dL, 9.51 to 12.40 g/dL, and 10.04 to 13.10 g/dL respectively. The P3-P97 reference range of healthy babies for Hb aged 1 month, 2 months, 3 months, and 4 months was 9.60 to 15.90 g/dL, 9.46 to 13.97 g/dL, 9.26 to 12.82 g/dL, and 10.00 to 13.33 g/dL respectively. This study also defined reference ranges for CBC, Ret-He, IRF, and RPI. The reference range of CBC, Ret-He, IRF, and RPI for healthy babies aged 1–4 months in this study can be used as a benchmark.
Perawakan pendek banyak dijumpai pada anak-anak di Indonesia. Perawakan pendek dapat merupakan suatu varian normal ataupun abnormal. Faktor yang dapat memengaruhi timbulnya perawakan pendek pada anak antara lain faktor genetik, nutrisi, hormon, penyakit, faktor psikologis, sosial ekonomi, dan lain-lain. Dampak perawakan pendek pada anak berupa gangguan kognitif, psikososial, dan kualitas hidup di kemudian hari. Short stature is common in children in Indonesia. Short stature can be a normal or abnormal variant. Many factors can cause short stature in children, including genetic, nutrition, hormones, diseases, psychological, socio-economic, etc. The impact of short stature on children includes decreased cognitive function, psychosocial, and quality of life.
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