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Dental evidence has been demonstrated as a major forensic tool for the identification of individuals and sex determination. The objective of the research was to determine sex in Delta Ibo ethnic group of Nigeria using the mandibular and maxillary canine teeth. Materials and methods. The study comprised 201 (100 males and 101 females) subjects of Delta Ibo ethnicity at the age of 17 – 25 years. The mesiodistal crown width and intercanine distance of both the maxillary and mandibular canines were measured intraorally using a pair of dividers and a ruler. Unpaired T-test at a probability value of p<0.05 was used to ascertain the mean significant differences between the male and female canine indices.   Results. Study results showed a statistically significant difference between male and female mandibular and maxillary canine mesiodistal width. This implied a sexual and reversed sexual dimorphism in the studied population.        Conclusions. The study confirmed that the canines of Delta Ibos exhibit sexual dimorphism like other populations and the maxillary canine indices give the most accurate prediction in sex determination.

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Bilateral transverse facial cleft, Tessier no 7 also known as bilateral congenital macrostomia are very rare clefts. We present an eight months old female with bilateral transverse facial cleft, third child of three siblings in a monogamous setting born to parents of Delta origin who resides in effurun Delta state of Nigeria. Mother ingested postinor several times in an attempt to abort pregnancy. Pregnant women should be encouraged to have adequate folic acid diet or supplements.

Cottonseed oil is an extract from the seeds of cotton plant, that is rich in protein, carbohydrate and fiber.          The objective of the research was to study the effect of cottonseed oil on the histology of the testis.          Materials and methods. Twelve adult male Wistar rats weighing 200 – 250g, were randomly sorted into four groups (I - IV), each containing three animals. Cottonseed oil was administered orally to the experimental animals by means of an orogastric tube. The rats in Group I (the control group) received standard rat pellet and oral normal saline ad libitum only. The animals in Groups II, III, and IV received 0.2 ml, 0.6 ml and 1.0 ml of cotton seed oil per body weight respectively. On the 21st day, the animals were sacrificed by cervical dislocation. The testes were excised and, then, fixed with appropriate fixatives for routine tissue processing.          Results. The results revealed an increase in the luminal diameter of seminiferous tubules, a decrease in the Leydig cell population, the disorientation of spermatogenic series and their detachment from the germinal epithelium.          Conclusions. The present study demonstrated that oral administration of cottonseed oil to male rats displayed a deleterious effect on their testis by disrupting spermatogenesis and the histological architecture of the testis.

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Malaria is an infectious disease caused by a single-celled parasite belonging to the genus Plasmodium. There are more than 100 different species but Plasmodium falciparum is the deadliest among humans. 1 Malaria threatens the lives of more than one-third of the world's population and it remains a major killer of humans worldwide. The disease exists mainly in the tropical areas of Asia, Africa, and America, where it infects millions of people. Each year, 350 to 500 million cases of malaria occur worldwide 2 and more than 1 million of its victims, mostly young children and pregnant women, die annually. 2,3 It is known that malarial infection is accompanied by increased production of reactive oxygen species (ROS) and the malarial parasites are sensitive to oxidative damage. 3 The univalent reduction of oxygen results in a series of cytotoxic oxygen species such as superoxide anions (O2-) , hydrogen peroxide (H2O2) and hydroxyl radicals (OH-). 4 These highly ROS can cause a wide-spectrum of cell damage including lipid peroxidation, inactivation of enzymes, alteration of intracellular oxidation-reduction state and damage to DNA. 5-7