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Purpose To identify whether the colon mucosa is affected by ten days of gastric restriction in an animal model. Methods An experimental model of gastric restriction was devised using rats. The animals were submitted to surgical gastrostomy, and a cylindrical loofah was inserted into the stomach. We studied 30 adult male Wistar rats divided into three groups: the stomach restriction group (R10); the sham group (S10), which underwent the same procedure except for the loofah insertion; and the control group (C10). The expression of neutral and acid mucins was evaluated using histochemical techniques. Goblet cells and protein content were compared between groups using generalized estimation equations (GEEs). Bonferroni’s multiple comparison was applied to identify differences between the groups. All tests considered a 5% significance level. Results There was an increased expression of neutral mucins, acid mucins and goblet cells in the R10 group. Collagen was also enhanced in the R10 group. Conclusion The colon mucosa is affected by ten days of gastric restriction in an animal model, increasing neutral mucins, acid mucins and collagen content with trophic maintenance.

BackgroundObesity and its related comorbidities have detrimental effects for the affected individual and pose a major challenge on public health systems worldwide.However, mechanisms of surgical weight loss and long‐term consequences of bariatric surgery remain unclear. Gastric reduction procedures are currently employed to treat morbid obesity and there are few reports concerning the consequent effects in large intestine.PurposeTo quantify the expression of neutral and acids mucins in mucosa of the colon in animal model and correlate this to gastric restrictionMethodsExperimental model of gastric restriction was devised using rats. The animals were submitted to surgical gastrostomy and a cylindrical loofah was inserted into the stomach. We studied 30 adult male Wistar rats divided in three groups: the stomach reduction group (R10), the sham group (S10), which underwent the same procedure except for the loofah insertion and the control group (C10). Animals were fed and kept in separate cages. They were weighed every other day until being sacrificed on day 10. The expression of neutral and acid mucins was evaluated using the histochemical techniques of Periodic Acid Schiff and Alcian Blue, respectively and Picrosirius Red. The tissue mucins and collagen expression were quantified by computer‐assisted image analysis software.Goblet cells and protein content were presented by groups as mean, median, minimum and maximum and it was compared between groups using generalized estimation equations (GEE) with normal distribution and identity link function supposing exchangeable correlation matrix between fields. Bonferroni's multiple comparison was applied to identify differences between groups. The results are described by the mean value with respective standard deviation. We used Spearman correlation to verify correlation between weight, height of the crypt and cells quantity. All tests were applied with 5% significance level.ResultsThere was increased expression of neutral mucins and acid mucins as well as Goblet cells in the R10 group. Picrosirius Red enhanced total collagen in restriction group.ConclusionsGastric restriction for 10 days in animal model increased neutral mucins and acid mucins as well as collagen content with trophic maintenance.This abstract is from the Experimental Biology 2019 Meeting. There is no full text article associated with this abstract published in The FASEB Journal.

A carta de brasão de armas do fidalgo de cota de armas Rui Gago da Câmara, de 1563, faz parte da coleção Brasões, do Arquivo Nacional, e é representativa da estrutura social da nobreza na transição do medievo para a modernidade. Segundo o direito heráldico português, essas cartas não estavam ao alcance de todos os nobres e somente lhes eram merecedores os fidalgos hierarquicamente superiores ao fidalgo de cota de armas. Entretanto, isso foi mudando com o tempo e sua concessão se intensificou. As cartas de armas eram diplomas manuscritos e ricamente iluminados, que concediam a um indivíduo o direito de usar as armas ou o brasão nelas pintado e traziam informações relevantes historicamente, tais como o nome, a naturalidade e a data de nascimento do armigerado, bem como a data da concessão das armas e a descrição heráldica e simbólica do brasão.

Pouco antes de partir para uma temporada de um ano na Universidade de Berkeley, nos Estados Unidos, o professor Ruy Gomes Braga Neto recebeu a Revista Plural em sua sala para uma entrevista, em agosto de 2010. Em uma conversa de pouco mais de uma hora, ele falou sobre sua formação fortemente influenciada pelo "caldo marxista da Unicamp"-segundo palavras do próprio autor-e sobre a relação entre suas pesquisas teóricas e empíricas. Ruy Braga nos falou também sobre as dificuldades do marxismo na atual conjuntura político-acadêmica e contou como se deu sua aproximação com a Sociologia pública, fazendo um convite para que os estudantes de Sociologia no Brasil se apropriem dessa nova agenda internacional de pesquisa. Revista Plural Gostaríamos de começar agradecendo por receber a Revista Plural para esta entrevista. Ruy Braga Sou eu que tenho que agradecer, gente! Revista Plural Gostaríamos que você falasse brevemente sobre sua formação. Ruy Braga Eu tenho uma formação acadêmica absolutamente concentrada em uma instituição, que é a Universidade Estadual de Campinas; quer dizer, eu fiz minha graduação, meu mestrado e meu doutorado na Unicamp... Eu, na verdade, entrei na Universidade de Campinas em 1990. Do meu período de formação, eu posso destacar duas coisas. A primeira delas é que a Unicamp, nesse momento do final dos 1980 e começo dos 1990-eu não sei como está hoje-, na época, era uma universidade muito vibrante e com uma Plural 17.1