Given the increase of women with excess weight or obesity and its possible effects on birth weight, the present study aimed to investigate the association between pregestational maternal body mass index (BMI) and birth weight in a birth cohort from Ribeirão Preto, SP, Brazil. This was a prospective study conducted on 1362 mother-child pairs involving singleton births. The women were evaluated using standardized questionnaires during the second trimester of pregnancy and at the time of childbirth. Information about the newborns was obtained from their medical records. The dependent variable was birth weight, categorized as low, adequate, or high. The independent variable was pregestational maternal BMI, categorized as malnutrition, adequate weight, overweight, and obesity. A multinomial regression model was used to estimate the crude and adjusted relative risk (RR) of low and high birth weight. A high frequency of pregestational excess weight (39.6%) was detected and found to be independently associated with high birth weight (RR=2.13, 95%CI: 1.19-3.80 for overweight and RR=3.34, 95%CI: 1.80-6.19 for obese pregnant women). There was no association between pregestational malnutrition and low birth weight (RR=1.70; 95%CI: 0.81-3.55). The present data showed a high rate of women with excess pregestational weight, supporting the hypothesis that pregestational BMI may contribute to high birth weight babies and indicating the need for actions aiming to prevent excessive weight in women at reproductive age.
A Síndrome de Silver-Russell (SSR) é uma patologia que apresenta heterogeneidade etiológica. Estudos têm demonstrado várias alterações cromossômicas correlacionadas ao fenótipo desta síndrome. Sua incidência varia de 1 caso em 3.000 nascimentos a 1 caso em 100.000 nascimentos. A SSR tem como principais características, o retardo no crescimento intra-uterino e pós-natal, assimetria corporal, idade óssea inferior, face triangular e baixa estatura persistindo até a idade adulta, entre outros. Em relação às manifestações intra-orais, destacam-se a micrognatia com palato duro ogival, língua sulcada e a microdontia. O objetivo do presente trabalho é apresentar um caso clínico de uma paciente com Síndrome de Silver-Russell atendida na clínica de Odontopediatria da FO/UFF, com a finalidade de alertar os cirurgiões-dentistas quanto à importância do tratamento precoce desses pacientes, devido aos problemas bucais associados, que os mesmos apresentam.Palavras-chave: Síndrome – Transtornos do Crescimento – Retardo do Crescimento Fetal
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