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Prediction of outcome in severe head injury based on recognition ofsleep related activity on the polygraphic electroencephalogram alternating pattern in the dynamic organisation of sleep.

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2Jansen, van der Naalt, van Zomeren, Paans, Veenma-van der Duin, Hew, et al combination with FDG-PET, and to use a neuropsychological testing battery suited for localisation.We thank Cygne BV for providing 55CoCl. Our special thanks to Mrs J Venema for secretarial assistance. This work was supported by a grant (GGN 22 2741) from the Dutch Technology Foundation (STW).

Mitochondrial respiration during recirculation after prolonged ischaemia in cat brain. Exp Neurol 1987;96: 321-33. 53 Wagner KR, Kleinholz M, Myers RE. Delayed decrease in specific brain mitochondrial electron transfer activities and cytochrome concentrations following anoxia/ ischaemia. J Neurol Sci 1990; 100: 142-51. 54 Wagner KR, Kleinholz M, Myers RE. Delayed onset of neurologic deterioration following anoxia-ischaemia coincides with appearance of impaired brain mitochon-drial respiration and decreased cytochrome oxidase activity.