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On Jeju Island, South Korea, an investigation was conducted to determine the best method for estimating Weibull parameters. Six methods commonly used in many fields of the wind energy industry were reviewed: the empirical, moment, graphical, energy pattern factor, maximum likelihood, and modified maximum likelihood methods. In order to improve the reliability of a research result, five-year actual wind speed data taken from nine sites with various topographical conditions were used for the estimation. Furthermore, the effect of various topographical conditions on the accuracy of the methods was analyzed and 10 bin interval types were applied to determine the most appropriate bin interval based on their performances. Weibull distributions that were estimated using these methods were compared with the observed wind speed distribution. Then the accuracy of each method was evaluated using four accuracy tests. The results showed that of the six methods, the moment method had the best performance regardless of topographical conditions, while the graphical method performed the worst. Additionally, topographical conditions did not affect the accuracy ranking of the methods for estimating the Weibull parameters, while an increase of terrain complexity resulted in an increase of discrepancy between the estimated Weibull distribution and the frequency of the observed wind speed data. In addition, the choice in bin interval greatly affected the accuracy of the graphical method while it did not depend on the accuracy of the modified maximum likelihood method.

Cervical cancer is a malignant neoplasm arising from cells that originate in the cervix uteri. It is the second most prevalent cancer among women. It can have several causes; an infection with some type of human papillomavirus (HPV) is the greatest risk factor for cervical cancer. Over 100 types of HPVs have been identified, and more than 40 types of HPVs are typically transmitted through sexual contact and infect the anogenital region. Among these, a number of HPVs types, containing types 16 and 18, are classified as "high-risk" HPVs that can cause cervical cancer. The HPVs vaccine prevents infection with certain species of HPVs associated with the development of cervical cancer, genital warts, and some less common cancers. Two HPVs vaccines are currently on the global market: quadrivalent HPVs vaccine and bivalent HPV vaccine that use virus-like particles as a vaccine antigen. This review discusses the current status of HPVs vaccines on the global market, clinical trials, and the future of HPVs vaccine development.

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To examine the applicability of the nacelle transfer function (NTF) derived from nacelle light detection and ranging (LIDAR) measurements to wind turbine power performance testing without a met mast, wind turbine power performance measurement was carried out at the Dongbok wind farm on Jeju Island, South Korea. A nacelle LIDAR was mounted on the nacelle of a 2-MW wind turbine to measure wind conditions in front of the turbine rotor, and an 80-m-high met mast was installed near another wind turbine to measure the free-stream wind speed. The power measurement instruments were installed in the turbine tower base, and wind speeds measured by the nacelle anemometer of the turbine were collected by the SCADA (Supervisory control and data acquisition) system. The NTF was determined by the table method, and then the power curve drawn using the NTF by the nacelle LIDAR (PCNTF, NL) was compared with the power curves drawn in compliance with International Electrotechnical Commission (IEC) standards, 61400-12-1 and 61400-12-2. Next, the combined standard uncertainties of the power curves were calculated to clarify the magnitude of the components of the uncertainties. The uncertainties of annual energy production (AEP) were also estimated by assuming that wind speed is a Rayleigh cumulative distribution. As a result, the PCNTF, NL was in good agreement with the power curves drawn in accordance with the IEC standards. The combined standard uncertainty of PCNTF, NL was almost the same as that of the power curve based on IEC 61400-12-2.

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