Given the lack of information concerning the role of Chlamydia trachomatis in male infertility, it has become imperative to analyse the quality of semen of male with seroevidence of antibody to Chlamydia trachomatis infection.

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The role of Chlamydia trachomatis in the pathogenesis of Pelvic inflammatory disease and majority of cases of salpinigitis are well acknowledged in women. A total of 213 sera from infertile women were tested for antibodies to Chlamydia trachomatis by using an indirect solid phases enzyme Immuno absorbent commercial ELISA test. Women with confirmed Hysterosalpinographic report suggesting tubal occlusion (tubal factor infertility) had 92 (43.2%) followed by 63 (29.6%) infertile women with infertile male partner and 58 (27.2%) were having unexplained infertility. Out of the tubal factor (TF) infertile women 40 (18.8%) were seropositive for Chlamydia trachomatis antibodies, as against 19 (8.9%) in the group of women with normal patent tubes and 10 (4.6%) women with infertile male partner. In this study there was a statistical significant correlation between the infertile women with tubal factor infertility in relation to seroevidence of Chlamydia trachomatis infection with p<0.05. There was no age bias in the serodetection of Chlamydia trachomatis antibodies. The seropositivity of Chlamydia trachomatis is an indication that the organism may be an independent risk factor in the development of an inflammatory process leading to scaring of the uterine tubes in women and thereby causing infertility.

Urogenital tract infection (UTI) contributes to the commonest single defined cause of infertility worldwide. To evaluate the role of urogenital tract infection in male with infertility and its association with sperm quality. Three hundred and twenty three (323) samples from infertile male subject were screened microbiologically for microorganisms associated with urogenital tract infection with seventy-two (72) age-matched male as a control using microbiological standard procedure.164 (50.8 %) infection rate was recorded. The dorminant uropathogen detected or isolated were staphylococcus aureus (14.0 %), Chlamydia trachomatis (11.4 %), Escherichia coli (4.3 %), Micoplasma genitalium (4.0 %) Klebsielli aerogenes (4.0 %). Others were Staphylococus saprophyticus, Pseudomonas aeruginosa, Protein mirabilis with 2.7 % each respectively, Protein vulgaria treponema pallidum (2.1 %), Schistosoma haematobium (0.9 %) Wulchereria Bancrofti (0.3 %), Human immune virus (2.7 %). Semen profile of the male patients with urogenital tract infection had abnormal semen quality in this study P<0.05. Oligospermic infertile male subjects should be screened for urogenital tract infection to further enhance good quality sperms and functions.