Seroevidence Of Chlamydia Trachomatis Infection In Infertile Male And Its Association With Semen Quality In University Of Benin Teaching Hospital, Benin City, Nigeria

Ibadin, KO; Enabulele, OI; Eghafona, N. O.; Osemwenkha, AP

doi:10.4314/bjpm.v11i1.48820

Cited by 5 publications

(5 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…C. trachomatis is known to be highly endemic in Nigeria with variation in distribution within various regions of the country (Okoror, 2010). The prevalence report of this study is close to 24 % among infertile males in Benin City (Ibadin et al, 2009), but quite less than 62.6% recorded by Okoror & Agbonlahor (2012), among infertile males in some parts of Nigeria. The prevalence in the current study is quite higher than 9.8% in Enugu, Nigeria (Ikeme et al, 2011).…”

contrasting

confidence: 39%

The prevalence of Chlamydia trachomatis infection among infertile males and its association with abnormal semen characteristics in Delta State, Nigeria

Osazuwa¹,

Aiguobarueghian²,

Alekwe

et al. 2013

Tanzania J Hlth Res

View full text Add to dashboard Cite

Chlamydia trachomatis is the most common cause of sexually transmitted diseases that is not of viral origin and there is accumulating evidence of a significant role played by this pathogen in causing male factor infertility. This study thus aimed to determine the prevalence of C. trachomatis among infertile males and to evaluate their association with fertility status and abnormal semen characteristics. This study included 215 infertile male subjects who visited a major fertility clinic in Warri, Delta state, Nigeria. Forty apparently healthy males without complaints of infertility were enrolled as controls. Blood samples were collected from patients aseptically using venous puncture and semen samples were obtained after masturbation. C. trachomatis IgG antibodies were assayed for in blood specimens using the Dot rapid Assay Kit flow through Ct cassette and positive samples were further screened with an enzyme immunoassay technique. Semen samples were analyzed following World Health Organization guidelines. Forty-two (19.5%) out of 215 infertile male subjects were found sero-positive for C. trachomatis. C. trachomatis was significantly associated with male infertility when compared to controls (P<0.001). Age groups 20-29 years (43.3%) and 30-39 years (22.1%) significantly had higher prevalence of C. trachomatis (P<0.001), as compared to age groups 40-49 (7.9%) and > 50 years (3.7%). Sero-positivity for C. trachomatis antibodies was significantly associated with oligozoospermia (22.5%) and azospermia (61.5%) than with teratozoospermia (7.3%) and asthenozoospermia (6.3%) (P<0.001). The prevalence of C. trachomatis among infertile males was high; there was an association between C. trachomatis infection and poor semen characteristics and infertility. There is need for routine screening for the pathogen in males with complaints of infertility so as to rule out this potentially correctable/reversible cause of infertility.____________________________________________________________________________________

show abstract

contrasting

confidence: 39%

The prevalence of Chlamydia trachomatis infection among infertile males and its association with abnormal semen characteristics in Delta State, Nigeria

Osazuwa¹,

Aiguobarueghian²,

Alekwe

et al. 2013

Tanzania J Hlth Res

View full text Add to dashboard Cite

show abstract

“…In an earlier study, Suominen et al, (1993) reported elevated levels of Chlamydia trachomatis as against 35 % observed in 28 oligospermia patients (Bjerke and Pourvis, 1992). Ibadin et al, (2009) observed 24 % out of 156 infertile male patients.…”

Section: Resultsmentioning

confidence: 99%

“…A similar conclusion about a bacterial reservoir function for the male was reached by other authors (Toth et al, 1996) that noted the incidence of vaginits, salpingitis, herpes and urinary tract infection in 1350 infertile couples and was generally higher in women whose husbands had reported a previous history of genitor-urinary infection. Another possibility is that Chlamydia trachomatis may influence infertility by inducing sperm autoantibodies (Soffert et al, 1990;Ibadin et al, 2009).…”

Section: Resultsmentioning

confidence: 99%

“…Infertility in males has also been associated with male accessory gland infections, mumps, tuberculosis and syphilis. Leukocytospermia of the epididymis and accessory sexual glands by Chlamydia trachomatis, Ureplasma urealyticum, and Mycoplasma genitalium have also been detected (Bukharin et al, 2003;Ibadin et al, 2009). In the light of the above submission, the objective of this study is to evaluate the male subjects with infertility for urogenital tract infections in relation to the semen quality and functions.…”

Section: Introductionmentioning

confidence: 98%

See 1 more Smart Citation

Urogenital Tract Infection in Asymptomatic Male Patients with Infertility in University of Benin Teaching Hospital, Benin City, Edo State

Ibadin¹,

Osemwenkha²,

Ibeh³

2012

MJM

View full text Add to dashboard Cite

Urogenital tract infection (UTI) contributes to the commonest single defined cause of infertility worldwide. To evaluate the role of urogenital tract infection in male with infertility and its association with sperm quality. Three hundred and twenty three (323) samples from infertile male subject were screened microbiologically for microorganisms associated with urogenital tract infection with seventy-two (72) age-matched male as a control using microbiological standard procedure.164 (50.8 %) infection rate was recorded. The dorminant uropathogen detected or isolated were staphylococcus aureus (14.0 %), Chlamydia trachomatis (11.4 %), Escherichia coli (4.3 %), Micoplasma genitalium (4.0 %) Klebsielli aerogenes (4.0 %). Others were Staphylococus saprophyticus, Pseudomonas aeruginosa, Protein mirabilis with 2.7 % each respectively, Protein vulgaria treponema pallidum (2.1 %), Schistosoma haematobium (0.9 %) Wulchereria Bancrofti (0.3 %), Human immune virus (2.7 %). Semen profile of the male patients with urogenital tract infection had abnormal semen quality in this study P<0.05. Oligospermic infertile male subjects should be screened for urogenital tract infection to further enhance good quality sperms and functions.

show abstract

“…The authors, however, concluded that C. trachomatis may be an independent risk factor affecting the quality of semen and male infertility. 35 Osegbe & Amaku 36 conducted a prospective study in Nigeria on the causes of male infertility using 504 patients. They concluded that the major causes were varicocele, infection, bilateral testicular failure, idiopathic oligospermia, multifactorial, cryptorchidism, sexual problems, and surgical injury.…”

mentioning

confidence: 99%

Causes and Risk Factors for Male Infertility: A Scoping Review of Published Studies

Okonofua¹,

Ntoimo²,

Omonkhua³

et al. 2022

IJGM

View full text Add to dashboard Cite

Background: Despite the evidence of declining sperm counts worldwide and the increasing prevalence of male infertility, there has been limited documentation of the potential causes and risk factors for male infertility. With limited methods of primary treatment of male infertility, understanding the causes and risk factors will pinpoint specific lines of prevention. Objective: We reviewed published studies on causes and risk factors for male infertility and identify gaps in the literature enabling more focused research and innovations. Design/Setting: The study was a scoping review. The review included studies on the causes and risk factors of male infertility published in scientific/academic publications. It was not limited to any region or date. The following databases were searched: Cumulative Index to Nursing and Allied Health Literature, Wiley online, HINARI, Science Direct, PubMed/Medline, Google Scholar, African Journals Online, and the WHO Repository. In total, 1295 articles were identified. After removing 357 duplicates, 938 articles were screened, and 71 articles were identified for inclusion, while 60 articles met the inclusion criteria. Results: Four broad causes and risk factors of male infertility identified were 1) biological/physiological/genetic causes, 2) behavioral/lifestyle risk factors, 3) environmental factors, and 4) socio-demographic risk factors. However, no substantive results on actual causes under each category were identified, leaving gaps for further research and experimentation. Conclusion:The results indicate limited knowledge of the actual causes of male infertility in published studies. The gaps in knowledge that need to be bridged to enable a fuller understanding of the actual causes of male infertility were highlighted.

show abstract

Seroevidence Of Chlamydia Trachomatis Infection In Infertile Male And Its Association With Semen Quality In University Of Benin Teaching Hospital, Benin City, Nigeria

Abstract: Given the lack of information concerning the role of Chlamydia trachomatis in male infertility, it has become imperative to analyse the quality of semen of male with seroevidence of antibody to Chlamydia trachomatis infection.

Cited by 5 publications

References 7 publications

The prevalence of Chlamydia trachomatis infection among infertile males and its association with abnormal semen characteristics in Delta State, Nigeria

The prevalence of Chlamydia trachomatis infection among infertile males and its association with abnormal semen characteristics in Delta State, Nigeria

Urogenital Tract Infection in Asymptomatic Male Patients with Infertility in University of Benin Teaching Hospital, Benin City, Edo State

Causes and Risk Factors for Male Infertility: A Scoping Review of Published Studies

Contact Info

Product

Resources

About