Background: Marginal tissue recession is a frequent clinical scenario that creates substantial compromise in esthetic appearance of the patient. The current randomized, double-blind interventional trial aims to evaluate the effectiveness of the combination of “platelet rich fibrin (PRF)” membrane with bioresorbable guided tissue regeneration (GTR) membrane as compared to GTR membrane alone utilizing “double lateral sliding bridge flap (DLSBF) technique” for the management of simultaneous GR defects in human subjects. Materials and Methods: Twenty subjects were randomly allotted in two groups: Group 1 (test): 10 subjects treated with PRF + GTR membrane using DLSBF technique and Group 2 (control): 10 subjects treated with GTR membrane alone using DLSBF technique. Clinical measurements such as relative gingival marginal level, “relative clinical attachment level (R-CAL),” “probing pocket depth (PPD),” “gingival recession (GR),” and “width of keratinized gingiva (WKG) and gingival thickness (GT)” were evaluated at the initiation of the study and 6 months thereafter. Results: Two groups showed statistically significant differences with respect to probing depth reduction, CAL gain, and increase in WKG and GT. No significant result was observed with mean root coverage (RC) and complete RC for test (84.80% ± 19.53% and 54.99% ± 38.53%) and control group (75.69% ± 18.86% and 35.83% ± 39.29%), respectively. Conclusions: The combination of PRF membrane used along with GTR membrane provides no additional benefits over GTR membrane alone. However, the DLSBF technique convincingly shows simultaneous elimination of multiple problems associated with GR, shallow vestibule, hypersensitivity, and aberrant frenum pull in a single stage with meticulous performance.
Background: In this evolutionary era of dentistry, newer techniques have evolved for complete coverage of multiple recession defects (MRDs). Since 2012, MRDs have been treated using the vestibular incision subperiosteal tunnel access (VISTA) approach and a variety of regenerating membranes with varying degrees of success. Platelet‑rich fibrin matrix (PRFM) membrane has shown a robust release of growth factors and was known to enhance the healing process. Thus, in this study we have evaluated the effectiveness of platelet-rich fibrin matrix (PRFM) with that of platelet-rich fibrin (PRF) membrane using the vestibular incision subperiosteal tunnel access (VISTA) technique in Miller Class I and II multiple gingival recession defects. Methods: This randomized, parallel designed, controlled, clinical study was conducted in 20 subjects (10 male and 10 female) having class I/II MGR defects either buccally or labially. The test group was treated with VISTA and PRF membrane while the control group was treated with VISTA and PRFM membrane. The clinical measurements such as plaque index, papillary bleeding index, probing pocket depth, relative attachment level (RAL) and relative gingival marginal level (R-GML), width of keratinized gingiva (WKG), gingival recession (REC) and gingival thickness (GT) were measured at baseline, three and six months. A Student’s paired t-test was utilized to analyse data from the day of surgery to six months. Results: Ten patients in the test group (89.23±15.04) and 10 patients in the control group (85.06±17.71) showed marked root coverage compared to baseline. Conclusions: Both test and control groups showed statistically significant enhancement in root coverage. However, no statistically significant difference was found when a comparison was made between the two groups in terms of PD, relative RAL, R-GML and REC reduction, gain in WKG, and increase in GT. Trial registration: CTRI/2021/07/035240, registered 29 July 2021.
Coronaviruses was discovered in the mid-1960s that affect humans. In 2019, Wuhan city of Hubei, China, there was an out-break of "coronavirus disease (COVID-19)" which is the result of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which is induced by a novel enveloped virus having single-stranded RNA. It transmitted rapidly affecting more than 200 countries globally, so, the World Health Organization has declared it as a pandemic. SARS-CoV-2 presently is a 7th amongst known coronaviruses that cause infection in people, after 229E and OC43 (earliest studied viruses in human patients suffering from a common cold). It has infected humans in all age groups, of all ethnicities, both males and females while spreading through communities at an alarming rate. Infected patients experience common cold-like symptoms along with raised temperature, non-productive coughing and difficulty to breathe. It is considered as a relative of severe acute respiratory syndrome (SARS) and the Middle East respiratory syndrome (MERS), COVID-19 is caused by a beta coronavirus named SARS-CoV-2, which affects the lower respiratory tract. Besides, SARS-CoV-2 also harms different organs. Till today, there is comprehensive knowledge about the extent and management of COVID-19-related disorders other than pulmonary system. The present review is an overview of systemic manifestations of COVID-19 that may affect gastrointestinal, cardiovascular, urinary, reproductive, hepatocellular or neurological systems.
Mouth rinses are therapeutic solutions utilized for gargling and rinsing the oral cavity. Several oral disorders need a mouth rinse, which can differ from halitosis to diseases of the periodontium. It is essential for the management of secondary infections, for example, oral mucositis. A mouth rinse may be suggested as an anti-inflammatory, antibacterial agent, topical analgesic, or for caries prevention. Several different mouth rinses are accessible nowadays. Selection of a suitable mouth rinse depends on the patient's requirement, disease threat and competence, and safety of mouth rinse. The application of antiseptics to the skin or mucous membranes before surgery or injections has been practised for many years. The goal of such an application is to reduce the number of microorganisms on the surface to prevent their entry into underlying tissues, which could cause bacteremia, septicemia, or harmful local infections. A similar idea of minimizing oral bacteria underlies the patient's usage of an antibiotic mouthwash before dental treatments. This decrease in microflora also reduces the possibility of pathogens entering the patient's mouth through direct contact, splatter, or aerosols during dental treatment. The main aim of this review is to aid oral health care professionals in making the correct selection of mouthwash while dealing with different conditions of the oral cavity.
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