The organic extracts of two licorices, known in commerce as Russian and Xinjiang licorices, exhibited potent antimicrobial and antioxidant activity. The bioassay-directed chemical investigation of both licorices revealed glabrene, glabridin, and licochalcones A and B as active principles.
A new isoflavan was isolated from the root of Glycyrrhiza glabra (licorice; Fabaceae), and its stmcture was elucidated as 8-prenyl-phaseollinisoflavan on the basis of spectroscopic evidence. Five known isoflavans have also been isolated, and identified with glabridin, 4'-0-methylglabridin, hispaglabridins A, B and what was previously elucidated as "3'-methoxyglabridin". The structure of the latter compound was revised to 3'-hydroxy-4-0-methylglabridin by an irradiation experiment and long range I3C-'H COSY spectral analysis.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.