Ultrafine bubbles stabilized by human serum albumin conjugate polyethylene glycol ameliorates the stability of complex as well as the drug payload. Polyethylene glycol presents the crucial role in releasing drug by means of acoustic sound.
As the SDS concentration increases in bubble rich solutions, the surfactant layer alters its size and refractive index. The scattered light enhancement and SFG signal cancellation prove that sub-monolayer adsorption exists at the air/water interface.
The
cause of the Jones–Ray effect has been controversially
debated for years. Ultrafine gas bubbles were employed to lessen the
surface excess of the surface-active impurities adsorbing to the air/water
interface of the salt solutions, which would lead to a direct shift
in surface tension observable by the Wilhelmy plate method. It was
concluded in this study that once the surface excess of the inevitable
impurities in the salts is lessened by the introduction of ultrafine
gas bubbles, which possess great air/water interfacial area, the Jones–Ray
effect becomes nonobservable. Therefore, our finding hypothesized
that the Jones–Ray effect might not originate from salts.
V. amygdalina (V.A) is an herb commonly used in folk medicine; it possesses various compounds with therapeutic capabilities. Traditional extraction approaches applied to this plant may destroy its bioactive compounds and inherently contaminate them with toxic organic solvents. In this study, ultrasound-assisted extraction combined with gas-bubble flotation was applied to increase V.A extraction yield. The efficiency of water maceration was increased by 200%, without the drawbacks of the conventional extraction methods. The total phenolic content yield was 189 ± 12.7 (mg GAE/g dry weight) with a condensation efficiency of 115 ± 5.7%; and the total flavonoid content was 6.44 ± 1.68 (mg QE/g dry weight). Additionally, the antioxidant activity of the condensed foam was enhanced up to 120%. Analysis of the extract by FTIR revealed the presence of extractable chemical families: sesquiterpene lactones, saponins and flavonoids, and that the chemical characteristics of the extract were also preserved This article is protected by copyright. All rights reserved. This is the author manuscript accepted for publication and has undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.