Lymphatic filariasis or elephantiasis is a vector borne disease caused by filarial worms that live in the lymph glands and lymph vessels of humans. W. bancrofti is the highest infection (90%) in the world. In urban areas, filariasis bancrofti was transmitted by Culex mosquitoes. Based on the health databases province, the number of people with filariasis in Central Java from 2011 to 2014 did not decline the cases. Based on the health profile of Regency / City in 2014, there are 23 cases of filariasis in Brebes regency, Central Java. One of the filariasis cases were found in the village of Dukuhturi, Bumiayu sub-district, Brebes. The survey of filariasis in Dukuhturi has never been done previously, therefore, this research conducted to observe of the biology of its vector and infection of filariasis in community. Culex sp. can be potentially as a vector is stated in many things, such as if was found microfilariae in the mosquito and the mosquito everbeen bite of the humans blood, it can be detected by the parousity mosquito in its ovaries. The aims of this research are to determine the parity rate of the mosquito, the prevalence of mosquitoes and villagers Dukuhturi were infected by microfilariae, and the density of microfilariae in respondents who infected by microfilariae. This research was conducted by using a survey method with cluster random sampling. Blood sampling performed by the ethical clearance and informed concent. The data were tabulated and analyzed descriptively based parousity of mosquitoes, the prevalence of mosquitoes and human who infected by microfilariae, and density of microfilariae in the human who infected by microfilariae. The result shows that parousity of mosquitoCulex sp. is high (94,45%) but the prevalence either in mosquito and respondent were 0%, so that the density of microfilariae is 0.Keyword: filariasis, parousity, prevalence, dencity of microfilariae. AbstrakFilariasis limfatik atau penyakit kaki gajah merupakan salah satu penyakit tular vektor yang disebabkan oleh cacing filaria yang hidup dalam kelenjar limfa dan saluran limfa manusia. Filariasis limfatik yang disebabkan Wuchereria bancrofti mendominasi hampir 90% infeksi di dunia.Di daerah perkotaan, filariasis bancrofti ditularkan oleh nyamuk Culex.Berdasarkan database kesehatan per Provinsi, jumlah penderita filariasis di Jawa Tegah dari tahun 2011 sampai 2014 tidak mengalami penurunan. Berdasarkan Profil kesehatan Kab/Kota 2014, di Kabupaten Brebes terdapat 23 kasus filariasis.Salah satu kasus filariasis tersebut ditemukan di Desa Dukuhturi, Kecamatan Bumiayu, Kabupaten Brebes yang kemungkinan ditularkan oleh nyamuk Culex sp. Survei mengenai filariasis belum pernah dilakukan di desa tersebut, oleh karena itu dilakukan survei terhadap darah tepi penduduk Desa Dukuhturi dan nyamuk Culex sp. sebagai vektornya. Nyamuk Culex sp. dapat berpotensi sebagai vektor filariasis jika ditemukan mikrofilaria di dalam tubuh nyamuk dan nyamuk pernah menghisap darah manusia, yang dapat diketahui dengan adanya kondisi parous (pernah...
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