We have studied changes in the IGF axis in an ovine model of myocardial infarction (MI), in order to determine the relationship between time-based changes in postinfarct myocardium and IGF levels. IGF localization was studied by immunocytochemistry, production by in situ hybridization, and specific binding by radioligand studies.
In January 1975 my wife Margaret and I stepped off a plane after backpacking around Europe in the months since we finished university the year before. We were handed two telegrams (they still had telegrams then). The first offered Margaret a job as a teacher in Hoxton Park in the western suburbs of Sydney. The second offered me a job with the Department of Defence in the Australian Public Service in Canberra. Frankly, I could not remember having applied for a job with the Department of Defence. Indeed I had spent the last few years at university 'railing against the machine' and protesting against what Rolling Stone magazine called the 'military-industrial complex'. To this day I suspect there had been a mix-up in the Defence recruitment mail room. My fit with Defence was, on the face of it, so poor that one of my startled friends asked which side I would be fighting for.
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