Due to the extensive differential diagnoses and overlapping clinical features, determining the aetiology of a crystalline retinopathy can be challenging. More effective ways are needed to help clinicians isolate the cause of a crystalline retinopathy and determine the appropriate management of concomitant ocular and/or systemic disease. This paper reviews literature on crystalline retinopathy focusing upon the key features of each aetiology, including medical history, laterality, and examination findings. Based on this review, an algorithm was formulated to clinically classify causes of crystalline retinopathy, which may help practising clinicians identify and manage key causes of crystalline retinopathy.
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