BACKGROUND: Medical students are frequently described as stressed in comparison with general population. 1,2 Particularly examinations are a major cause of stress. 3 High level of stress may have adverse effect on academic achievement. However there is a deficit of information regarding the interrelationship of stress and academic performance in medical students. The present study adds to the literature of the level of stress during examination and its impact on performance in a cohort of first year medical students. The study also discusses the areas where medical students are more stressful, effects of stress, student's adaptation styles, and intervention measures to deal with stress, as it is believed that healthy medical students are likely to become healthy doctors who can then be model and promote healthy lifestyles with their patients. 4 AIMS AND OBJECTIVES: 1. To determine the effect of stress measured by self-evaluation questionnaire. 2. Impact of examination stress on the academic performance of first year medical students. 3. To study effect of premenstrual stress on autonomic function. MATERIAL AND METHODS: A prospective cohort study was conducted on medical students to determine the examination stress measured by anxiety questionnaire and autonomic function tests. One hundred medical students studying in first academic year admitted for the first year during 2011-2012 in S.P. Medical College, Bikaner. Stress was measured during first terminal examination since it was the first major examination faced by the students after entering into the professional course. SUMMARY AND CONCLUSION: In consort with previous research, the examination of first year medical students is stressful enough to affect the performance adversely. Since stress around examinations is strongly predicting the academic achievement, students should be exposed to stress management techniques to help prevent the known high consequences.
<p style="text-align:justify;"> <span style="font-size:10.0pt;font-family:;" "="">The present study was designed to explore the possible mechanism of obesity associated metabolic syndrome. 150 subjects (120 men and 30 women) in the age-group of 17 - 26 years were studied. Body Mass Index and Waist-to-Hip Ratio were taken as a measure of generalized obesity and abdominal adiposity. The serum concentration of glucose-6-phosphate dehydrogenase increased with increasing levels of Body Mass Index and was found to be significant in obese subjects (Body Mass Index ≥ 30.0 kg/m<sup>2</sup>) and more so in the obese subjects with abdominal adiposity (p = 0.002) as compared to normal-weight subjects. Karl Pearson coefficient of correlation revealed a significant positive correlation of glucose-6-phosphate dehydrogenase with Body Mass Index (r = 0.499; p < 0.001) and malondialdehyde (a biomarker of oxidative stress) (r = 0.736; p < 0.001) but inverse correlation with adiponectin (r = -0.524; p < 0.001). Thus, we conclude that increased expression of glucose-6-phosphate dehydrogenase in obese subjects (more if it is associated with abdominal adiposity) might mediate the onset of obesity associated metabolic disorders by increasing oxidative stress.</span> </p>
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