The monofunctional bidentate Schiff base ligand (o-vanillin)p-chloroaniline and its four new complexes of chromium(III), cobalt(II), nickel(II) and copper(II) have been synthesized by classical thermal and microwave-irradiated techniques. All the new derivatives have been characterized by elemental analysis, molecular weight determinations, molar conductance measurements, UV-Vis, IR and NMR spectral studies. The IR spectral data suggest the involvement of phenolic oxygen after deprotonation and azomethine nitrogen in coordination to the central metal ion. The growth inhibiting potential of the ligands and complexes has been assessed against a variety of fungal and bacterial strains.
AbstractNatural polymers are being investigated with renewed exuberance as they have a tremendous unexploited potential. During the past few decades, much interest has developed in the biopolymer-based materials due to their biodegradable, nontoxic, biocompatible and non-allergic nature. Chitosan (CS) is the second most abundant naturally occurring amino polysaccharide after cellulose and is extracted from the shells of sea crustaceans. The primary amine group in CS is responsible for its various properties and it is derived from the deacetylated form of chitin. Its biocompatible, nontoxic, biodegradable and antimicrobial properties have led to significant research towards biomedical applications, such as tissue engineering, wound healing, drug delivery, obesity treatment, etc. This review summarizes the present work done by researchers in prospects of CS and its numerous applications in the biomedical field.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.