Structural, Spectroscopic and Biological Aspects of O, N‐ Donor Schiff Base Ligand and its Cr(III), Co(II), Ni(II) and Cu(II) Complexes Synthesized through Green Chemical Approach

Rathore, Kavita; Singh, Rajiv Kumar; Singh, Harjinder

doi:10.1155/2010/521843

Cited by 12 publications

(7 citation statements)

References 14 publications

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“…This band shifted to lower frequencies of about 50 cm -1 in the metal complexes, suggesting coordination through the C=N of the benzothiazole ring. This is further supported by the emergence of bands around 485-482 cm -1 in the metal complexes assigned to M-N 22,23 . The bands at 1077, 1056 and 1056 cm -1 in the ligand, [Ce(SBC)2(H2O)2](SO4)2 and [Nd(SBC)2(H2O)2](NO3)3, respectively were assigned to the thiocarbonyl group 19 .…”

Section: Conductivity Measurementsmentioning

confidence: 60%

Synthesis, Characterization and Biological Studies of S-1,3-Benzothiazol- 2-ylthiophene-2-carbothioate and Its Ce(IV) and Nd(III) Complexes

Oruma¹,

Ukoha²,

Asegbeloyin³

2014

Asian J. Chem.

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S-1,3-Benzothiazol-2-ylthiophene-2-carbothioate (SBC) was synthesized by the S-acylation of 2-mercaptobenzothiazole with thiophene-2-carbonylchloride in the presence of pyridine. Its Ce(IV) and Nd(III) complexes were also synthesized. The ligand and its Ce(IV) and Nd(III) complexes were characterized by UV-visible, IR and GC-MS spectroscopy. In addition, the ligand was characterized based on its 1 H and 13 C NMR data and the metal complexes based on conductivity measurement and stoichiometric ratio of combination. The infrared spectral study of S-1,3-benzothiazol-2-ylthiophene-2-carbothioate and its Ce(IV) and Nd(III) complexes gave evidence for coordination through the nitrogen of the benzothiazole ring and carbonyl oxygen. All the complexes were found to contain coordinated water and were assigned octahedral geometry. Antibacterial screening of the compounds were carried out in vitro on Gram-positive bacteria (Bacillus subtilis and Staphylococcus aureus) and Gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa). The compounds showed significant activities against Gram-positive bacteria than Gram-negative bacteria. However, the ligand showed more chemotherapeutic efficacy than the complexes. The compounds were not active against Pseudomonas aeruginosa. Synthesis of S-1,3-benzothiazol-2-ylthiophene-2carbothioate:The ligand was prepared by S-acylation of 2mercaptobenzothiazole with thiophene-2-carbonylchloride in the presence of pyridine which acts as a catalyst 11 . To a solution of 2-mercaptobenzothiazole (2.51 g, 0.015 mole), thiophene-2-carbonylchloride (1.60 mL, 0.015 mole) was added followed by 5 mL of pyridine. The mixture was heated with stirring over a water bath until fumes of hydrogen chloride ceased to appear. About 2 mL of distilled water was added, followed by 2 mL of pyridine to eliminate the excess reagent. The product solidified upon stirring with a glass rod into a white coloured solid. Water (10 mL) was added, the product filtered and recrystallized from dilute ethanoic acid. The yield was 40.38 % and the melting point 162 °C. The spectral results are as follows: UV (λmax nm, cm -1 ) (ethanol): (256, 271, 336); (13, 845,14,657,18,172). IR (KBr, νmax, cm -1 ): 3054 (s), 2985 (m), 1670 (m), 1560 (m), 1497 (m), 1420 (s), 1077 (s), 896 (s), 738 (sh), 706 (w). 1 H NMR (CDCl3) (δ, ppm): 7.15 (1H, d), 7.20 (2H, t), 7.23 (1H, d), 7.25-7.40 (4H, m). 13 C NMR (δ, ppm): 112. 551, 121.412, 124.622, 127.232, 130.365, 141.002, 191.212. Syntheses of Ce(IV) and Nd(III) complexes:The complexes were synthesized by refluxing ethanol solutions of Ce(SO4)2 and Nd(NO3)3·5H2O with the ligand, respectively in amounts equal to metal: ligand molar ratio of 1:2 to ensure complete reaction 6,7 . To ethanolic solution (20 mL) of cerium(IV) sulphate (0.32 g, 0.004 mole) was added a solution of S-1,3benzothiazol-2-ylthiophene-2-carbothioate (2.22 g, 0.008 mole) in ethanol (40 mL). The mixture was refluxed for 1 h under constant stirring at 80 °C. On cooling, milk coloured precipitate formed. They were filtere...

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Section: Conductivity Measurementsmentioning

confidence: 60%

Synthesis, Characterization and Biological Studies of S-1,3-Benzothiazol- 2-ylthiophene-2-carbothioate and Its Ce(IV) and Nd(III) Complexes

Oruma¹,

Ukoha²,

Asegbeloyin³

2014

Asian J. Chem.

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“…The absence of bands around 10120-11605, 16062-16180 and 25210 -25575cm -1 assignable to, respectively are due to charge transfer transitions from ligand to Ni(II) ion [23][24][25]. The electronic spectrum of cobalt (II) oxidized to Co(III) complex a d 6 ion consists of three bands in the region 25000, 29851 and 38462 cm -1 .…”

Section: Uv-vis Data and Metal-ligand Mole Ratiomentioning

confidence: 99%

“…The complexation process increased as temperature increased for all the metal ions until at a maximum of about 35 o C. The increased complexation of the metal ions to the ligand at relatively high temperatures (between [20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35] o C) showed that the complexation process may be endothermic [33]. From table II, Gibb's free energy change values were found to be negative indicating the feasibility and spontaneity of the complexation.…”

Section: Thermodynamics Of Complexationmentioning

confidence: 99%

Spectral and thermal analysis study of some transition metal complexes derived from bis(2,2/-methylylidene phenol)diaminoethane

Nworie¹

2017

SDRP-JCCMM

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The thermodynamics of complexation and thermal properties of mixed ionic complexes of the types M(H 2 L)X 2 and M(HL)X (where M = Fe(II), Fe(III),Co(III), Ni(II), and Cu(II)., L = bis(2,2 / -methylylidenephenol) diaminoethane, and X = anions of the types Cl -, NO 3 -, SO 4 2-, ClO 4 -or OH -) prepared using extractive method have been investigated. Thermal decomposition of the transition metal complexes took place in two or three distinct steps in exothermic reaction up to 800°C. The heat capacity change ( ), transition midpoint temperature (T m ), entropy change ( ), calorimetric enthalpy , Gibbs free energy change ( ), denaturation enthalpy ( )) and denaturation entropy ( ) were calculated from the results of differential scanning calorimetry (DSC) while Vant Hoff thermodynamic properties was used to calculate the stability constants of the complexes in solution.

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“…Kloramfenikol digunakan sebagai kontrol untuk penghambatan pertumbuhan mikroba. Hasil yang ditunjukkan dari pengujian aktivitas antibakteri adalah baik karena semakin besar konsentrasi senyawa Schiff base, maka semakin besar pula zona diameter hambatnya, hal ini menunjukkan bahwa senyawa tersebut memiliki aktivitas antibakteri yang baik dikarenakan senyawa Schiff base sebagai donor atom (O dan N), 9 sehingga gugus hidroksil meningkatkan aktivitas biologi. 3 Gugus C=N pada Schiff base dapat bersifat sebagai antibakteri di mana gugus amina (NH 2 ) mempunyai elektron bebas.…”

Section: Pendahuluanunclassified

Synthesis and Characterization of Antimicrobial Fe (III) and Derivat Schiff Base Complex

Sirumapea¹,

Asmiyanti²,

Khoirunisa

2015

IJPST

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Reaksi antara amina primer dengan karbonil menghasilkan basa Schiff (Schiff base) yang secara teori memiliki sifat antibakteri. Sifat antibakteri ini dapat ditingkatkan dengan pembentukan kompleks Schiff base dengan logam tertentu. Telah dilakukan sintesis senyawa Schiff base dan kompleksnya dari 4,4-diamino difenil eter, ortohidroksi benzaldehid dan ion logam Fe (III). Senyawa Schiff base dan kompleks yang terbentuk dikarakterisasi gugus fungsinya dengan spektrometer FT-IR. Senyawa yang terbentuk kemudian diuji aktivitas antibakterinya terhadap bakteri Staphylococcus aureus menggunakan metode difusi agar. Spektra senyawa Schiff base mempunyai puncak pada bilangan gelombang 1620,21 cm-1 dan spektra senyawa kompleks mempunyai puncak pada bilangan gelombang 1612,49 cm-1. Puncak pada senyawa Schiff base mengindikasikan adanya ikatan CH=N, pergeseran puncak pada kompleks Schiff base menunjukkan adanya ikatan antara nitrogen dengan ion logam. Hasil pengujian senyawa Schiff base dan kompleks terhadap bakteri S. aureus menunjukkan positif sebagai antibakteri S. aureus.

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Structural, Spectroscopic and Biological Aspects of O, N‐ Donor Schiff Base Ligand and its Cr(III), Co(II), Ni(II) and Cu(II) Complexes Synthesized through Green Chemical Approach

Cited by 12 publications

References 14 publications

Synthesis, Characterization and Biological Studies of S-1,3-Benzothiazol- 2-ylthiophene-2-carbothioate and Its Ce(IV) and Nd(III) Complexes

Synthesis, Characterization and Biological Studies of S-1,3-Benzothiazol- 2-ylthiophene-2-carbothioate and Its Ce(IV) and Nd(III) Complexes

Spectral and thermal analysis study of some transition metal complexes derived from bis(2,2/-methylylidene phenol)diaminoethane

Synthesis and Characterization of Antimicrobial Fe (III) and Derivat Schiff Base Complex

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