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Perhydrolase S54V (AcT) effectively catalyzes the perhydrolysis of propylene glycol diacetate (PGD) to generate peracetic acid (PAA). PAA is a potent oxidant used for sanitization and disinfection, with broad effectiveness against bacteria, yeasts, fungi, and spores. In this study, active and stable composites are developed by incorporating AcT–carbon nanotube conjugates into polymer and latex‐based paint. At a conjugate loading of 0.16% (w/v), the composite generated 11 mM PAA in 20 min, capable of killing more than 99% spores initially charged at 106 colony‐forming units per milliliter.

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COVER PICTUREThe cover picture shows a ligand-targeted proteinase enzyme or ™catalytic antagonist∫ acting as a molecular angler fish: By precisely positioning different binding ligands (L) around the active site ™mouth∫ of a degradative proteinase enzyme, target proteins (TP) can be plucked from solution, locked in position adjacent to the catalytic triad ™jaws∫, and in this way readily and specifically degraded. The hunting strategy of the deep sea angler fish, which uses a lure above its mouth, illustrates this principle. Further details can be found in the article by B. Davis, R. R. Bott, J. B. Jones et. al. on pp. 533 ± 537. REVIEWS Don't get stressed! Stress is often linked by anecdote to degeneration and disease. Key molecular, cellular and medical evidence is described in this review that gives firm support for this linkage and suggests that key stress hormones such as cortisol or corticosterone acting in synergy with the action of cytokines (see figure) may trigger and/or promote many diseases.N. Lozovaya, A. D. Miller* ± 484Chemical Neuroimmunology: Health in a NutshellChemBioChem is a European journal of chemical biology; it is co-owned by a group of European scientific societies and published by WILEY-VCH. Contributions in ChemBioChem cover chemical biology and biological chemistry, medicinal chemistry, bioinorganic and bioorganic chemistry, biochemistry, molecular and structural biology, that is, research of the overlapping areas between biology and chemistry.

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