TECHNOLOGY UPDATE: Development of a gas-phase bioprocess for isoprene-monomer production using metabolic pathway engineering

Whited, Gregory M.; Feher, Frank J.; Benko, David A.; Cervin, Marguerite A.; Chotani, Gopal; McAuliffe, Joseph C.; LaDuca, R J; Ben-Shoshan, Eliahu A.; Sanford, Karl

doi:10.1089/ind.2010.6.152

Cited by 196 publications

(186 citation statements)

References 27 publications

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“…The polymer has traditionally been extracted from rubber trees, but nowadays more than 800,000 t/a isoprene is produced via petrochemistry for polymerization to synthetic rubber and elastomer. 67,68 In nature, isoprene is formed by various microbial, plant, and animal species. Plants emit it in massive amounts, estimated at 600 million t/a, into the atmosphere.…”

Section: Isoprenementioning

confidence: 99%

Transformation of Biomass into Commodity Chemicals Using Enzymes or Cells

2013

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Section: Isoprenementioning

confidence: 99%

Transformation of Biomass into Commodity Chemicals Using Enzymes or Cells

2013

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“…The BioIsoprene TM strategy involves the fermentation of sugars, such as glucose, or other biomass, with engineered bacteria. 80 This continuous process produces gaseous isoprene that is recovered and purified for polymerization. 81 As shown in Figure 8, the production of BioIsoprene TM involves the metabolism of glucose with recombinant E. coli through two possible pathways.…”

Section: Isoprenementioning

confidence: 99%

“…80 The bio-based polyisoprene, referred to as BioNatsyn TM had Mooney viscosity (71) values and glass transition temperatures (T g ¼ À61 C) which were very similar to petroleum-based polymers.…”

Section: Isoprenementioning

confidence: 99%

How well can renewable resources mimic commodity monomers and polymers?

Mathers

2011

J. Polym. Sci. A Polym. Chem.

221

100

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This highlight discusses the recent progress aimed at maximizing the potential of biomass for commodity monomers and polymers. These efforts are no longer solely academic issues. In recent years, a variety of alkene, diene, aromatic, and condensation type monomers have utilized renewable resources, such as cellulose, lignin, plant oils, starches, and monoterpenes in commercial polymers. Generally, these multifaceted efforts involve pretreatment of biomass with thermal, chemical, or physical methods followed by a catalyst sequence that entails a combination of acid-catalysis, bio-catalysis, or metal-based catalysis. In this regard, synthesis strategies for ethylene, propylene, a-olefins, methylmethacrylate, 1,3-butadiene, 1,3-cyclohexadiene, isoprene, 1,3-propanediol, 1,4-butanediol, and terephthalic acid are discussed as well as opportunities for other renewable-based monomers. V C 2011 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 50: [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15] 2012

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“…Isoprene is being produced starting from renewable resources due to the successful metabolic engineering of the isoprene pathway. 45 escalate and show volatility, there is an economic incentive to fi nd alternative routes to traditional materials. Great progress has been made in recent years in developing alternative routes to traditional materials, starting with renewable resources.…”

Section: Traditional Polymers Made From Renewable Resourcesmentioning

confidence: 99%

“…Genencor has pioneered the metabolic engineering of the isoprene pathway to express it in E. coli , thus resulting in an industrial biochemical process that produces high purity isoprene. 45 This renewably resourced isoprene is also being incorporated into tires; a schematic is shown in Figure 6 .…”

Section: Traditional Polymers Made From Renewable Resourcesmentioning

confidence: 99%