Our findings suggest that HLA-B*15:02 is significantly associated with OXC-SJS in Asian populations (Chinese and Thai). However, the severity and incidence of OXC-SJS/TEN are less than that of CBZ-SJS/TEN. The need for preemptive HLA-B*15:02 screening should be evaluated further.

Cutaneous mucinoses encompass a variety of cutaneous disorders. Cutaneous focal mucinosis (CFM) was originally described as an asymptomatic solitary lesion characterized by abundant focal cutaneous mucin deposits. However, multiple focal mucinous lesions associated with systemic diseases have also been designated as CFM. Our clinicopathological study of 11 cases of solitary lesions confirmed that CFM is a unique primary cutaneous mucinosis unrelated to mucinosis-associated systemic diseases. We suggest calling this group of CFM lesions "solitary CFM" to distinguish them from multiple CFM associated with mucinosis associated systemic diseases. Our cases showed slight male predominance with a median age of 50 years. They occurred most often on the extremities (45%), presented as asymptomatic solitary, white to erythematous, small, soft, fibroma-like lesions. None of the clinical impressions were of CFM. We call attention to include solitary CFM in clinical differential diagnosis of polypoid skin lesions.

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