Two new cyclic dipeptides, rhinocladin A (1) and rhinocladin B (2), were isolated from a fungal endophyte (Rhinocladiella sp. lgt-3) of Tripterygium wilfordii Hook. Their structures were elucidated by 1D and 2D NMR spectra. The monoamine oxidase inhibitory activity of 1 and 2 was also evaluated.
Wortmannolol (1), a new furanosteroid, along with five known compounds, wortmannolone (2), ergosterol (3), p-hydroxyphenyl ethanol (4), trans-6-dodecene (5), (2Z, 4E) -5-(8-hydroxy-1,5-dimethyl-3-oxo-6-oxabicyclo [3.2.1] octan-8-yl) -3-methylpenta-2,4-dienoic acid (6) were isolated from a fungal endophyte Talaromyces sp. lgt-4. Their structures were elucidated by IR, MS, 1D and 2D NMR spectra. Compound 1 show weak monoamine oxidase inhibitory activity.
Secovironolide, a Novel Furanosteroid Scaffold with a Five-Membered B Ring from the Endophytic Fungus Talaromyces wortmannii LGT-4. -Two novel compounds, secovironolide (I) and epoxyvirone (II), together with five known viridian derivatives are isolated from the title fungus. -(DING, H.-E.; YANG*, Z.-D.; SHENG, L.; ZHOU, S.-Y.; LI, S.; YAO, X.-J.; ZHI, K.-K.; WANG, Y.-G.; ZHANG, F.; Tetrahedron Lett. 56 (2015) 48, 6754-6757, http://dx.
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