The aim of this study was to investigate the occurrence of Leishmania spp. antibodies, and its association with feline immunodeficiency virus (FIV) and feline leukemia virus (FeLV), in domestic cats from an area endemic for canine and human leishmaniasis in Rio Grande do Norte State, Brazil. Ninety-one cats were subjected to a complete clinical exam, and blood samples were collected. An epidemiological questionnaire was used to investigate the risk factors. IgG anti-Leishmania spp. antibodies were detected by immunofluorescence antibody test (IFAT), with a cut-off value of 1:40. Polymerase chain reaction (PCR) was performed to detect genetic material of Leishmania spp. in the blood samples. The presence of antibodies against FIV and antigens of FeLV was evaluated using an immunochromatographic test. Seropositivity for Leishmania spp., FIV, and FeLV was observed in 14/91 (15.38%), 26/91 (28.57%), and 3/91 (3.29%) cats, respectively. All samples gave negative results on PCR analysis. Based on these data, no significant statistical association was observed between seropositivity for Leishmania spp., and sex, age, presence of clinical signs, evaluated risk factors, and positivity for retroviruses. These findings demonstrated for the first time that cats from Mossoró, Rio Grande do Norte, are being exposed to this zoonosis and might be part of the epidemiological chain of transmission of visceral leishmaniasis.

An epidemiological survey aiming to determine the occurrence of anti-Leptospira antibodies and to identify risk factors was carried out in horses of the Pajeú microregion, state of Pernambuco. Sera from 100 horses from 38 properties in four counties in the region were examined by the microscopic agglutination test (MAT), using 24 Leptospira spp. serovars as antigens. Of the 100 samples tested, 28 (28%) were positive. Most prevalent serovars were Patoc (35.71%), Butembo (32.14%) and Sentot (14.30%). Supply of pasture as forage (odds ratio =7.80; 95% confidence interval - 95%CI 1.71-35.50; p=0.008) was identify as risk factor. It is suggested the need for studies on agent isolation and characterization of its pathogenicity, as well as it is recommended the rodent control in deposits of feed and environment.

RESUMO: O objetivo deste estudo foi analisar a influencia do banho 24 horas antes do procedimento cirúrgico e da tricotomia pré-operatória na redução da contagem microbiana da pele do campo operatório, bem como a eficiência antisséptica do gluconato de clorexidina 0,5% e da polivinilpirrolidona iodada 10% para antissepsia do sítio cirúrgico, verificando sua ação 4 minutos e 2 horas após aplicação. Utilizaram-se 20 cadelas hígidas, alocadas ao acaso em 2 grupos de 10 animais: os animais do Grupo I foram submetidos ao banho 24 horas antes do procedimento cirúrgico, enquanto os do Grupo II não passaram por este procedimento. Foram isolados diversos gêneros bacterianos antes e após o uso dos antissépticos. Significância estatística foi verificada entre os grupos quanto ao efeito do banho prévio à cirurgia, apenas 2 horas após a aplicação de clorexidina. A tricotomia reduziu 26,48% da carga microbiana nos animais do Grupo I e elevou a carga microbiana em 41,19% nos animais do Grupo II, revelando diferença estatística. Após o uso dos antissépticos, não foi observada diferença estatística entre os grupos em nenhum momento. Do mesmo modo, a comparação da eficiência dos antissépticos com ou sem banho, não revelou significância estatística. A polivinilpirrolidona iodada causou reação alérgica em 15% dos animais e não foi observada irritação cutânea causada pela clorexidina. Conclui-se que o banho prévio tem efeito na redução da carga bacteriana apenas após 2 horas de antissepsia com clorexidina; a tricotomia é mais eficaz na redução microbiana quando o animal é submetido ao banho e os dois antissépticos são igualmente eficazes na antissepsia cirúrgica por até 2 horas quer o animal tome banho ou não previamente à cirurgia.

ResumoA mucocele sublingual é uma afecção incomum em cães, porém de grande importância para a medicina veterinária, devido aos prejuízos gerados por suas consequências. Deste modo, o presente relato tem como objetivo descrever o caso de mucocele sublingual em cão com posterior recidiva em glândula mandibular e sublingual, bem como discutir sua importância para a medicina veterinária. Foi atendido no Hospital Veterinário Dix-Huit Rosado Maia -HOVET/ Universidade Federal Rural de Semiárido (UFERSA), um cão macho, com um ano e 10 meses de idade, apresentando aumento de volume bilateral na região sublingual há, aproximadamente, dois meses. Após exame clínico suspeitou-se de mucocele da glândula sublingual bilateral (rânula) indicando-se o tratamento de ressecção da glândula sublingual esquerda devido ao aspecto nodular e marsupalização da glândula sublingual direita. Passado um mês da alta médica o animal retornou ao HOVET -UFERSA com queixa de aparecimento de um novo aumento de volume sublingual e na região cervico-ventral suspeitando-se de uma possível mucocele cervical e recidiva da mucocele sublingual esquerda. Indicou-se como tratamento a sialoadenectomia sublingual e mandibular. Cerca de dez dias após a última cirurgia o cão não apresentava mais aumento de volume da área afetada e não havia sinais de alteração quanto à produção de saliva. O tratamento sugerido proporcionou bons resultados promovendo a reparação tecidual e reestruturação do local afetado e diminuindo o índice de recidiva.Palavras-chave: glândula salivar, marsupialização, mucocele. AbstractThe sublingual mucocele is a rare disease in dogs, but very important for veterinary medicine due to losses generated by its consequences. Thus, this report aims to describe the case of sublingual mucocele in a dog with subsequent relapse in mandibular and sublingual gland and discuss their importance to veterinary medicine. It was the Veterinary Hospital Dix-Huit Rosado Maia -HOVET / Universidade Federal Rural de Semi-árido (UFERSA), a male dog with one year and 10 months, an increase of bilateral volume in the sublingual region for approximately two months. After clinical examination was suspected of mucocele of bilateral sublingual gland (ranula) indicating the treatment of sublingual left gland resection due to nodular and marsupalização the right sublingual gland. After one month of a medical release the animal returned to HOVET -UFERSA with emergence of complaint from a further increase in sublingual volume and cervical-ventral region suspecting it is a possible cervical mucoceles and recurrence of sublingual mucocele left. It is stated as a treatment to sublingual and mandibular sialoadenectomy. About ten days after the last surgery, the dog had no more swelling of the affected area and no signs of change with saliva production. However, the suggested treatment provided good results by promoting tissue repair and restructuring of the affected area and decreasing the recurrence rate.

The aim of this study was to assess systemic and neurotoxic changes following an epidural administration of meloxicamin to rabbits. Twelve adult rabbits four males and eight females; average mass, 1.9 ± 0.1kg were randomly divided into two groups: a control group (GC), which received a single dose of 0.9% NaCl epidurally in a volume of 0.3mL kg-1and a meloxicam group (GM), which received 0.2mg kg-1 meloxicam epidurally along with 0.9% NaCl in a total volume of 0.3mL kg-1. Heart rate, respiratory rate, body temperature, and neurological abnormalities were assessed prior to administration of anesthesia (H0), 1, 2, 3, 6, 12, and 24h following epidural puncture (H1, H2, H3, H6, H12, and H24, respectively), and every 24h afterward for 10 days after epidural puncture (D2, D3, D4, D5, D6, D7, D8, D9, and D10). The surface temperature of lumbosacral region was also measured at H0, H1, H6, H12, H24, D5 and D10. Three animals from each group were euthanized on days 15 and 30 after epidural puncture to assess possible spinal injuries. Variances observed in physiological parameters were not suggestive of adverse effects of meloxicam, as all were within the reference standards, and there were no physical or behavioral changes observed. Neurological function was similar between groups, with only difference between baseline values and values 1h after epidural administration in both groups. There were no histopathological changes in the GM group, and only one animal showed discrete lymphocytic infiltrate. Epidural lumbosacral administration of meloxicam at a dose of 0.2mg kg-1 caused no significant systemic or neurotoxic effects in rabbits.

We compared the analgesia and cardiopulmonary changes induced by epidural methadone or fentanyl in combination with lidocaine in female dogs undergoing elective ovariohysterectomy and anesthetized with propofol. Eighteen female dogs were randomly assigned to two groups and given either methadone (0.3 mg kg?¹) + 2% lidocaine without vasoconstrictor (LM) or fentanyl (5 µg kg?¹) + 2% lidocaine without vasoconstrictor (LF). The drugs were administered epidurally in a volume of 0.25 ml kg?¹. Heart rate (HR), respiratory rate (RR), rectal temperature (RT), systolic blood pressure (SBP), and blood glucose levels were recorded before and 15 minutes after premedication (T0 and T1); 15 minutes after epidural administration (T2); five minutes after dermotomy (T3); five minutes after clamping of the ovarian pedicle (T4); five minutes and 1, 3, 6, 12, 18, and 24 hours (T5, T6, T7, T8, T9, T10, and T11, respectively) after surgery. The number of additional propofol injections and total propofol dose (mg kg?¹) were recorded. Analgesia was assessed using a numerical descriptive scale. SBP and HR were similar in both groups, but hypotension was detected in animals from both groups at different times. Respiratory rate decreased significantly at T6 in the LF group and was lower than in the LM group. Hypothermia was observed in animals from both groups, but RT was significantly lower than baseline values only at T4 in the LM group. Blood glucose levels increased significantly only in the LF group at T4, T7, and T8. All animals in the LF group and eight animals in the LM group required additional propofol injections at T4, but no significant differences were detected in the number of propofol injections and total propofol dose between the LF (3 ± 1 injections, 7.5 ± 4.5 mg kg?¹) and LM (2 ± 2 injections, 4.5 ± 3.4 mg kg?¹) groups. The latency period, anesthetic period, and the duration of surgery were similar in both groups. No animals required rescue analgesia. The lidocaine-methadone and lidocaine-fentanyl combinations caused minimal cardiorespiratory changes, but did not abolish pain at the time of handling of the ovarian pedicle.

INTRODUÇÃO: A medicina do plasma tem despontado como uma tecnologia em saúde viável e resolutiva na cicatrização de feridas. OBJETIVO: Comparar o efeito do modo contínuo e pulsado de aplicação do plasma atmosférico frio na cicatrização de feridas cutâneas agudas em porquinhos da índia. MÉTODOS: Foram utilizados 24 animais divididos em quatro grupos e submetidos a realização de 3 feridas no dorso, sendo ao mesmo tempo, experimento e controle segundo aprovação da CEUA (parecer nº 33/2020). Uma ferida foi controle, outra recebeu tratamento no modo contínuo e outra pulsado (10 Hz). O jateamento foi de 1 minuto em cada ferida com gás hélio 2L/ min, imediatamente após a cirurgia e a cada 24 horas por 3 dias consecutivos. Todas as feridas foram fotografadas a partir do dia 0 e analisadas no software Image J. Além do processamento histológico. RESULTADO: A média da taxa de retração das feridas controle nos dias 3, 7, 14 e 21 foi 30,91; 38,5; 89,16; 96,32. Já no grupo contínuo foi de 45,36; 51,95;91,40; 98,13. E no pulsado 54,20; 57,5; 95,74; 99,1, respectivamente. A taxa de retração dos grupos tratados foi significativamente maior que no controle. No dia 7, foi possível visualizar o processo de reepitelização, que se completou no dia 14 nas feridas tratadas com a epiderme e o estrato córneo espessos. No grupo controle, foi possível visualizar isto a partir do dia 14 e a epiderme e o estrato córneo estavam delgados. Não foi mais encontrado tecido de granulação nos tecidos tratados no dia 14, e no controle encontrou-se nos dias 14 e 21. DISCUSSÃO: de maneira geral a literatura aponta para um efeito benéfico do CAP no processo de cicatrização de feridas tanto quantitativamente, como qualitativamente. CONCLUSÃO: O uso do CAP promoveu uma redução do tempo e melhora qualitativa no processo de cicatrização.

The objective of this study was to evaluate the replacement of a growth-promoting antibiotic by fennel (Foeniculum vulgare) and citronella (Cymbopogon winterianus) essential oils in the quail diet on performance variables (weight gain, feed intake, feed conversion), as well as the carcass and cut yield. To do so, 240 one-day-old male and female European quails were distributed in a completely randomized design with four treatments, five replications and 12 animals per experimental unit. The treatments consisted of: PC – positive control diet without fennel or citronella essential oils and with the growth promoter (zinc bacitracin); NC – negative control diet without essential oils and without growth promoter; CEO - Diet with +0.078% citronella essential oil without the growth promoter; and FEO - Diet with +0.078% fennel essential oil without the growth promoter. The experiment lasted 42 days, in which the performance variables were analyzed in three periods (1-14 days; 14-21 days; and 22-42 days) and the carcass and cut yield in two periods (at 21 and 42 days). The observed data were submitted to analysis of variance and the comparison of means was performed using the Tukey’s test at 5% significance. The presence of essential oils positively influenced (P<0.05) the performance variables and the carcass and cuts yield in all analyzed periods. The use of fennel and citronella essential oils to replace zinc bacitracin in the diet of European quails improves performance and the carcass and cut yield.