Background: One of the subdisciplines of Ashtanga Ayurveda is known as Agadatantra, and it deals with the various conditions associated with poisoning as well as their diagnosis and treatment. Sarpavisha is the most important Visha because it is the condition that requires urgent assistance. There are many Agada Yogas (anti-poisonous formulations) that are helpful in Sarpavisha Chikitsa mentioned by Ayurvedic Acharyas. Sugandhadi Agada is one of the Agada Yogas mentioned by Acharya Vagbhatta in Ashtanga hridye and Acharya Vriddha Vagbhatta in Ashtanga Sangraha. Aim and objectives: Based on the function of Sugandhadi agada's ingredients as described in various classical texts, this review and debate will focus on Mandali snake bite poisoning. Materials and Method: By focusing on its properties and mechanism of action, the comprehensive review of Sugandhadi Agada formulation is done using texts like Ashtanga Hridye and Ashtanga Sangraha. Observations and Results: Sugandhadi Agada, as described by Acharya Vagbhatta and Vriddha Vagbhatta, contains eight drugs, all of which have Vishahara, Jwarhar, raktapittahar, and Shothohara properties and can be used to treat Mandali Sarpavisha. Conclusion: Sugandhadi Agada, as mentioned by Acharya Vagbhatta and Acharya Vridda Vagbhata in Mandali Sarpavisha Chikitsa, might be one of the effective anti-poisonous formulations that ought to be tried for experimental and clinical trials in Sarpavisha Chikitsa. Key words: Agada Tantra, Sarpadamsha Chikitsa, Sugandhadi Agada, Mandali Sarpavisha
Introduction: Opium and its derivative addiction are one of the most prevalent addictions in western Rajasthan, because it is easily available and is being used openly in social programs as the culture of the same. In western Rajasthan, mainly Doda poppy, opium milk, smack, tramadol, etc. are major forms of opium-derived addictions. Withdrawal symptoms such as nausea, vomiting, diarrhea, chills, body ache, sleeplessness and flu-like symptoms begin, these symptoms can grow severe enough to necessitate emergency medical attention, and in extreme situations, they might have life-threatening consequences for the user as a result of respiration depression, and pupil dilation in the later stages. The assessment was based on Clinical Opiate Withdrawal Scale (cows) before and after the treatment. Intervention: Efforts have been applied to depict 8 cases of opium addiction in form of series who have been treated with Ahiphenmochanadi vati in the dose of 250 mg twice a day and Sameergaja kerari rasa in the tapering method (Padanshika Krama) starting with the dose of 375 mg along with panchakarma procedures, Shirodhara with til tail, Abhayanga, and Swedana with Mahanarayan Tail and Dashmool kwath respectively for a period of 1 month. Reduction in cows scale was observed, about 75-80% of symptoms subsided in all cases and the results have been reported very encouraging within a period of twenty to thirty days. Conclusion: Altogether, multimodal Ayurveda treatment can be an effective and safe solution for smack addictions.
Bioaccumulation and biomagnification are the main process through which environmental toxicity takes place in living organism. This era is era of modernisation and urbanisation and environmental toxicity has become the most dangerous situation. In Ayurveda with the explanation of human health and diseases, the same importance was given to environment and other living creature also. In Ayurveda, environmental toxicity is explained as Janapadodhwansa. Four main factors are explained under Janapadodhwansa - Vayu (air), Jala (water), Desha (land), and Kaala (season) and these becomes more dangerous in following order. Many formulations and method are explained for these Janapadodhwansa factors. Some researches has been done on these method and formulation and some on other herbs and formulation. For eg- Dhoopan Karma with Laksha, Haridra and other drugs is explained as best remedy for the air pollution. Research study on Dhoopan Karma had given the promising result. Ash of some herbs are told to mix with the polluted water. To store water, copper metal and mud made vessels are told in Ayurveda. Research has proved that copper vessel makes water bacteria free. Soil pollution now a days is due to waste of metals and chemicals. Researches has found that the level of metal contamination can be minimised by use of herbs like Neem. The main protocol of management of disease occurred due to environmental pollution is to follow the moral and ethics and Panchakarma.
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