We implement imaging spectroscopy of the optical clock transition of lattice-trapped degenerate fermionic Sr in the Mott-insulating regime, combining micron spatial resolution with submillihertz spectral precision. We use these tools to demonstrate atomic coherence for up to 15 s on the clock transition and reach a record frequency precision of 2.5×10^{-19}. We perform the most rapid evaluation of trapping light shifts and record a 150 mHz linewidth, the narrowest Rabi line shape observed on a coherent optical transition. The important emerging capability of combining high-resolution imaging and spectroscopy will improve the clock precision, and provide a path towards measuring many-body interactions and testing fundamental physics.
This study identifies a frontline mechanism comprising autonomy, cohesion, and feedback that helps explain when and why the simultaneous pursuit of quality and productivity orientations has positive or negative effects on unit revenue, efficiency, and customer satisfaction. An empirical test of the proposed framework using data from 423 employees in 30 strategic business units and longitudinal unit-level performance data indicates that frontline autonomy mediates the positive impact of productivity and quality orientations on unit revenue and customer satisfaction and their negative impact on unit efficiency. Feedback amplifies the influence of frontline autonomy by simultaneously enhancing its positive effect on satisfaction and its negative effect on efficiency. In contrast, unit cohesion strengthens the positive effect of frontline autonomy on revenue and customer satisfaction without augmenting its negative effect on unit efficiency. The results urge managers to shift their focus toward unit-level mechanisms to find clues for managing strategic dilemmas that stem from multiple goal pursuit in face-to-face service settings.
Electrolyzed reduced water, which is capable of scavenging reactive oxygen species, is attracting recent attention because it has shown improved efficacy against several types of diseases including diabetes mellitus. Alloxan produces reactive oxygen species and causes type 1 diabetes mellitus in experimental animals by irreversible oxidative damage to insulin-producing b-cells. Here, we showed that electrolyzed reduced water prevented alloxaninduced DNA fragmentation and the production of cells in sub-G1 phase in HIT-T15 pancreatic b-cells. Blood glucose levels in alloxan-induced type 1 diabetes model mice were also significantly suppressed by feeding the mice with electrolyzed reduced water. These results suggest that electrolyzed reduced water can prevent apoptosis of pancreatic b-cells and the development of symptoms in type 1 diabetes model mice by alleviating the alloxan-derived generation of reactive oxygen species.Keywords Electrolyzed reduced water Á Alloxan Á Type 1 diabetes mellitus Á Reactive oxygen species Á HIT-T15 cells
:
The possible beneficial properties of functional foods are due to their content in bioactive ingredients, with
specific biological properties. A number of processed functional foods are available in the market – probiotic yogurt,
calcium and ω-3 fatty acids enriched orange juice and milk. Simultaneously, new research studies confer potential health
benefits of various conventional foods (salmon, berries, green tea, vegetables, fruits, nuts, cereals and breads etc) termed
as “superfood” which is a marketing term and there is no established medical definition. Following suitable dietary
patterns superfood reduces the risk of degerative diseases by promoting physical and emotional health. Scientific
evidences suggests that superfood are dense source of antioxidants, minerals, vitamins and other nutrients. There is
insufficient research on the exact explanation of term ‘superfood’and its health claims by different companies without any
legislation. This buzz word making confusion among consumers, that how much and what quantity should make a food
superfood, as no single food may be as nutritious to be stated as superfood. This article introduces further investigation on
superfood which was categorized on the basis of their major constituents and potential health benefits. Further there is a
need of more reviews, researches, clinical trials and human case studies to investigate or test superfood.
It has been demonstrated that hydrogen peroxide (H(2)O(2)) is directly associated with elevated matrix metalloproteinase-2 (MMP-2) expression in several cell lines. Electrochemically reduced water (ERW), produced near the cathode during electrolysis, and scavenges intracellular H(2)O(2) in human fibrosarcoma HT1080 cells. RT-PCR and zymography analyses revealed that when HT1080 cells were treated with ERW, the gene expression of MMP-2 and membrane type 1 MMP and activation of MMP-2 was repressed, resulting in decreased invasion of the cells into matrigel. ERW also inhibited H(2)O(2)-induced MMP-2 upregulation. To investigate signal transduction involved in MMP-2 downregulation, mitogen-activated protein kinase (MAPK)-specific inhibitors, SB203580 (p38 MAPK inhibitor), PD98059 (MAPK/extracellular regulated kinase kinase 1 inhibitor) and c-Jun NH(2)-terminal kinase inhibitor II, were used to block the MAPK signal cascade. MMP-2 gene expression was only inhibited by SB203580 treatment, suggesting a pivotal role of p38 MAPK in regulation of MMP-2 gene expression. Western blot analysis showed that ERW downregulated the phosphorylation of p38 both in H(2)O(2)-treated and untreated HT1080 cells. These results indicate that the inhibitory effect of ERW on tumor invasion is due to, at least in part, its antioxidative effect.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.