A case of rhinofacial zygomycosis with of years duration, caused by Conidiobolus coronatus is described. The patient, a 72-years-old woman, presented with a bilateral distortion of the subcutaneous tissue and disfigurement of the face. Treatment with ketoconazole and potassium iodide did not prevent several relapses. At present she is still under treatment with fluconazole with clinical healing. Histopathological and mycological examination confirmed the dermatological diagnosis. An increasing number of cases of zygomycosis caused by fungi of the order Entomophthorales have also been reported in the Northern and Northeastern States of Brazil.
Background
Chronic leg ulcers affect a large portion of the adult population and cause a significant social and economic impact, related to outpatient and hospital care, absence from work, social security expenses, and reduced quality of life. The correct diagnosis and therapeutic approach are essential for a favorable evolution.
Objective
To gather the experience of Brazilian dermatologists, reviewing the specialized literature to prepare recommendations for the diagnosis and treatment of the main types of chronic leg ulcers.
Methods
Seven specialists from six university centers with experience in chronic leg ulcers were appointed by the Brazilian Society of Dermatology to reach a consensus on the diagnosis and therapeutic management of these ulcers. Based on the adapted DELPHI methodology, relevant elements were considered in the diagnosis and treatment of chronic leg ulcers of the most common causes; then, the recent literature was analyzed using the best scientific evidence.
Results
The following themes were defined as relevant for this consensus - the most prevalent differential etiological diagnoses of chronic leg ulcers (venous, arterial, neuropathic, and hypertensive ulcers), as well as the management of each one. It also included the topic of general principles for local management, common to chronic ulcers, regardless of the etiology.
Conclusion
This consensus addressed the main etiologies of chronic leg ulcers and their management based on scientific evidence to assist dermatologists and other health professionals and benefit the greatest number of patients with this condition.
Pili torti also known as ‘twisted hairs’ (Latin:
pili=hair; torti=twisted) is a rare, congenital
or acquired clinical presentation, in which the hair shaft is flattened at irregular
intervals and twisted 180º along its axis. It is clinically characterized by fragile,
brittle, coarse and lusterless hairs, due to uneven light reflection on the twisted
hair surface. Pili torti may be associated with neurological
abnormalities and ectodermal dysplasias. There is no specifi c treatment for this
condition, but it may improve spontaneously after puberty. We report a case of
pili torti in a child who presented fragile, brittle, diffi cult
to comb hair. The patient had no comorbidities.
This case report details how melphalan and prednisone can be administered in the successful treatment of necrobiotic xanthogranuloma with lambda paraproteinemia.
Three monthly pulses of azithromycin 500 mg for 3 consecutive days is safe, well tolerated, effective and promotes increased patient adhesion to the treatment.
Traumatic neuromas are tumors resulting from hyperplasia of axons and nerve sheath
cells after section or injury to the nervous tissue1. We present a case of this tumor, confirmed by anatomopathological
examination, in a male patient with history of circumcision. Knowledge of this entity
is very important in achieving the differential diagnosis with other lesions that
affect the genital area such as condyloma acuminata, bowenoid papulosis, lichen
nitidus, sebaceous gland hyperplasia, achrochordon and pearly penile papules.
É apresentado caso de lúpus eritematoso bolhoso na infância. Doente do sexo feminino, com nove anos, apresentava erupção vesicobolhosa no tronco, região cervical, genital e membros. O exame anatomopatológico mostrou bolha subepidérmica com neutrófilos, a imunofluorescência direta revelou depósito linear de IgA, IgM, IgG e C3 na zona da membrana basal, e a indireta foi negativa. Os anticorpos antinucleares e o anti-Sm estavam positivos. Houve regressão do quadro com dapsona e prednisona. Trata-se de caso raro de lúpus eritematoso sistêmico (LES) na infância que se iniciou com bolhas disseminadas. O LES bolhoso deve ser incluído no diagnóstico diferencial das erupções bolhosas na infância.
Tinea nigra, a relatively uncommon mycosis caused by Phaeoannelomyces werneckii, is typically seen as an asymptomatic brown or black macule on the hands and feet. We present two cases of tinea nigra in children in São Paulo, Brazil, and alert readers to the potential for confusion with melanocytic lesions.
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