Traumatic neuromas are tumors resulting from hyperplasia of axons and nerve sheath
cells after section or injury to the nervous tissue1. We present a case of this tumor, confirmed by anatomopathological
examination, in a male patient with history of circumcision. Knowledge of this entity
is very important in achieving the differential diagnosis with other lesions that
affect the genital area such as condyloma acuminata, bowenoid papulosis, lichen
nitidus, sebaceous gland hyperplasia, achrochordon and pearly penile papules.
Pityriasis Rubra Pilaris (PRP) is a chronic and rare papulosquamous disorder.
Treatment of Pityriasis Rubra Pilaris is based on empiric evidence because of
several doubts regarding its etiology and also because of its relative rarity,
making randomized studies difficult to perform. Some factors suggest that the
metabolism of vitamin A is involved in pathogenesis. We report a case of
Pityriasis Rubra Pilaris associated with autoimmune hypothyroidism which
presented rapid and complete response after thyroid hormone replacement, without
any association with other systemic treatment. In literature there are only
three other reports of significant improvement of the lesions after hormonal
correction. Deficiency of thyroid hormone inhibits the conversion of carotene
into vitamin A, which would be responsible for the occurrence of Pityriasis
Rubra Pilaris in this patient.
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