This study shows that in Ricaurte the carrier frequencies of FMR1 expanded alleles (premutations and FMs) are higher than those reported in the literature, suggesting that Ricaurte constitutes a genetic cluster of FXS.
The diagnosis of functional gastrointestinal disorders (FGIDs) centers on symptoms-based criteria (Rome criteria). The last edition of the criteria was published in 2016. Still, few data on its validity support its use in children. We conducted a study aimed at determining the diagnostic accuracy of the Rome IV criteria through the application of questionnaires (Questionnaire of Pediatric Gastrointestinal Symptoms-Rome IV QPGS-IV) to diagnose FGIDs in children. We hypothesized that the Rome IV criteria has adequate diagnostic accuracy supporting its use for diagnosing FGIDs in children. Methods: School children ages 10 to 18 years from Cali (Colombia) completed the Spanish version of the QPGS-IV. Children with FGIDs were matched with a group of children without FGIDs. Both groups had a medical consultation with a blinded experienced pediatric gastroenterologist (criterion standard) who provided his diagnosis. The questionnaire-based diagnoses were compared with the consultation's diagnoses. Results: Of 487 schoolchildren surveyed with the QPGS-IV, 97 (20.8%) had FGIDs. Eighty-nine with FGIDs were matched with 92 children without FGIDs (mean age 13.1 years [±1.3]). We found a higher prevalence of FGIDs during the medical visit than using the self-report QPGS-IV (66.3% vs 49.2%, P = 0.001), mainly in abdominal pain disorders (19.3% vs 10.5%, P = 0.013). The Rome IV diagnostic criteria using the QPGS-IV had a sensitivity of 75% (95% confidence interval, 59–79) and 90% specificity (95% confidence interval, 83–98). Positive predictive value is 85.8%, and negative predictive value is 79.9%. Conclusion: Our study suggests that the QPGS-IV has adequate diagnostic accuracy.
Varela-Arévalo MT, Ochoa-Muñoz AF, Tovar-Cuevas JR. Tipologías de estilos de vida en jóvenes universitarios. Univ. Salud. 2016;18(2):246-256. DOI: http://dx.doi.org/10.22267/rus.161802.35 Resumen Introducción: La evidencia actual sobre la relación entre los estilos de vida y las principales problemáticas de salud mundial es amplia, dando cuenta del aumento en las cifras de comportamientos de riesgo y de sus impactos en la salud de la población. Objetivo: Identificar agrupaciones entre los jóvenes matriculados en una universidad privada de Cali, a partir de ocho dimensiones relacionadas con sus estilos de vida. Materiales y métodos: Se aplicó el Cuestionario de Estilos de Vida de Jóvenes Universitarios, que permitió clasificar las prácticas de los jóvenes en saludables y no saludables a 370 estudiantes con edades entre 18 y 25 años. Se utilizaron modelos de regresión para respuesta binaria y una combinación de métodos factoriales con análisis de conglomerados para obtener tipificación de estilos de vida. Se trabajó con ayuda de los paquetes Stats para los modelos de regresión y FactoClass para el análisis multivariado con el software R. Resultados: Fue posible establecer tres conformaciones tipológicas: 1) hombres sin pareja, que no trabajan, con prácticas no saludables en actividad física; 2) mujeres sin pareja, que no trabajan, con prácticas no saludables de actividad física y alto nivel de estrés; 3) mujeres sin pareja, que no trabajan, con prácticas no saludables de actividad física. Conclusiones: Las tipologías encontradas permitirán a la universidad realizar intervenciones focalizadas que consideren las características propias de diferentes tipos de jóvenes, logrando mejores resultados y optimizando los recursos disponibles.Palabras clave: Conductas saludables; adultos jóvenes; análisis de regresión; género y salud; salud del adolescente. (Fuente: DeCS, Bireme). AbstractIntroduction: The current evidence on the relationship between lifestyles and the main health problems in the world is wide, taking into account the increase in the numbers of behaviors of risk and their impacts on the health of the population Objetive: The aim of the study was to describe life styles of private college youth from Cali, according to their practices in eight dimensions, and to identify clustering of them. Materials and methods: The study sample consisted of 370 youth with ages between 18 and 25 years, who answered the Lifestyle Questionnaire for University Students -CEVJU-R2, which classifies healthy and unhealthy practices. Regression models for binary response factor and a combination of cluster analysis methods were used. The stats packages for the regression models and FactoClass
Assessing healthy habits related to child overweight and obesity is important concerning the prevention efforts. A variety of measures to assess eating habits and physical activity are available, being the self-report frequency questionnaires the most common and cost-efficient. Nevertheless, those questionnaires generate a large amount of data. Considering this, the purpose of the study was to develop a proposal to synthesize information from the Child Overweight/Obesity Healthy related Habits Questionnaire (CHS-SO), through the creation of indexes and a combination of a factorial method and cluster analysis. Nine indexes were created to assess eating habits, physical activity, and digital entertainment use, allowing to classify children into healthy or unhealthy in each index. The CHS-SO was administered to 239 children between 8 and 12 years old from Cali, Colombia. Data obtained from the indexes were analyzed using a multiple correspondence analysis and cluster analysis. Results show that most of the children have healthy eating habits, physical activity was lower in girls and digital entertainment use was high.Resumen Evaluar los hábitos de salud relacionados con el sobrepeso y la obesidad infantil resulta fundamental para la prevención de estas problemáticas. Existe una amplia variedad de instrumentos para medir dichos hábitos, siendo más comunes y costo-eficientes los cuestionarios de autorreporte, sin embargo estos generan información demasiado extensa y difícil de analizar. Por tanto, este estudio tuvo como objetivo desarrollar una propuesta de síntesis de la información obtenida del Cuestionario de Hábitos de Salud relacionados con el Sobrepeso/Obesidad Infantil (CHS-SO), a partir de la construcción de indicadores de hábitos de alimentación, de actividad física y de consumo de entretenimiento digital que permitan clasificar a los niños como saludables o no saludables. Participaron 239 niños y niñas de 8 a 12 años de edad, quienes completaron el CHS-SO. La combinación del análisis de correspondencias múltiples con el de conglomerados arrojó dos clústers. Los hábitos de alimentación fueron saludables en la mayoría de los niños, sin embargo fueron identificadas diferencias en función del sexo y el nivel socioeconómico. Por el contrario, los dos hábitos menos saludables fueron el comer mientras se emplean dispositivos de entretenimiento digital y el tiempo destinado a estos últimos.
Introducción/Objetivo: Establecer el nivel de adherencia de un grupo de mujeres trans colombianas a las medidas de prevención ante el SARS-CoV-2. Método: Diseño transversal correlacional descriptivo de una sola etapa. Se administró un cuestionario en línea anónimo a 100 mujeres trans de Colombia. Los resultados fueron obtenidos utilizando métodos estadísticos tanto frecuentistas como bayesianos (a priori- a posteriori). Resultados: Cerca de las tres cuartas partes de las mujeres participantes reportaron un alto nivel de adherencia a las conductas preventivas. Los factores asociados fueron sentirse capaz de implementar las acciones de prevención y creer en la eficacia de ellas, para evitar contagiar a otros, los conflictos con otras personas y problemas legales. Conclusiones: La autoeficacia y los comportamientos gobernados por reglas están relacionados con la adherencia a las medidas de prevención. Abordar la adherencia en tiempos de COVID-19 implica incorporar de manera integral la magnitud de las inequidades e injusticias sociales y las respuestas en salud ante una situación que afecta a la humanidad de manera diversa y diferenciada.
This paper considers the use of classical and Bayesian inference methods to analyze data generated by variables whose natural behavior can be modeled using asymmetric distributions in the presence of left censoring. Our approach used a Lèvy distribution in the presence of left censored data and covariates. This distribution could be a good alternative to model data with asymmetric behavior in many applications as lifetime data for instance, especially in engineering applications and health research, when some observations are large in comparison to other ones and standard distributions commonly used to model asymmetry data like the exponential, Weibull or log-logistic are not appropriate to be fitted by the data. Inferences for the parameters of the proposed model under a classical inference approach are obtained using a maximum likelihood estimators (MLEs) approach and usual asymptotical normality for MLEs based on the Fisher information measure. Under a Bayesian approach, the posterior summaries of interest are obtained using standard Markov chain Monte Carlo simulation methods and available software like SAS. A numerical illustration is presented considering data of thyroglobulin levels present in a group of individuals with differentiated cancer of thyroid.
Tuberculosis (TB) represents a health problem in Colombia, and its control is focused on the search for contacts and treatment of TB cases underscoring the role of latent tuberculosis infection (LTBI) as a reservoir of Mycobacterium tuberculosis. The burden of LTBI in Colombia is unknown. We aimed to estimate the prevalence of LTBI and identify the associated risk factors. In this cross-sectional study, we recruited participants from four health care centers in Cali, Colombia. The participants were eligible if they were aged between 14 and 70 years, and all participants answered a survey evaluating their medical history and sociodemographic and lifestyle factors. LTBI status was based on tuberculin skin test (TST) positivity using two thresholds: ≥10 mm (TST-10) and ≥15 mm (TST-15). The magnitude of the associations between independent factors and dependent outcomes (LTBI status and TST induration) were evaluated by logistic regression and generalized linear models, respectively. A total of 589 individuals were included with TST positivity rates of 25.3% (TST-10) and 13.2% (TST-15). Logistic regression showed that being between age 40 and 69 years (OR = 7.28, 95% CI [1.62–32.7]), being male (OR = 1.71, 95% CI [1.04–2.84]), being employed (OR = 1.56, 95% CI [1.02–2.38]), and having a low intake of alcohol (OR = 2.40, 95% CI [1.13–5.11]) were risk factors for TST positivity, while living in the north zone (OR = 0.32, 95% CI [0.18–0.55]), living in the suburb zone (OR = 0.28, 95% CI [0.15–0.52]) and having a secondary education (OR = 0.49 95% CI [0.29–0.83]) lowered the risk of TST positivity. The generalized linear model showed that the previous predictors, as well as a low body mass index, had an effect on TST reaction size. The LTBI prevalence found in the population was moderate, reflecting the continuous transmission of M. tuberculosis. Social factors seem to play a decisive role in the risk of LTBI. Employed males, who are over 40 years of age, are overweight, have a lower level of education and have a low intake of alcohol (50–100 mL, once/week) should be a priority group for prophylactic treatment as a strategy for TB control in this city.
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