A number of puppies of the School Hospital of the Faculty of Veterinary Science-UBA showed bone changes. Measurement of the iodine content of the commercial diet showed a significant increase in its content. Iodine excess causes alterations in thyroid function and morphology, and its hormones have a direct action on bone formation. Three groups of puppies were fed on different diets: a home-prepared diet, a commercial diet (containing 5.6 mg potassium iodide/kg dry food), and a home-prepared diet supplemented with 5.6 mg potassium iodide/kg dry food. Groups B and C developed hypothyroidism. A significant decrease (p<0.05) in the styloid apophyseal surface was found in groups B and C vs. A, determined by radiography. Histologically, the hypertrophied cartilage was shorter in groups B and C than in group A (p<0.0001). The present results suggest that commercial diets with a high iodine content may cause hypothyroidism and changes in bone metabolism.
PAPERS & ARTICLES the use of tetracyclines (Walton and others 1983) and the availability ofpotentiated amoxycillin as a liquid preparation may make it preferable for the treatment of chlamydiosis in young kittens. Chlamydiosis in cats can be treated successfully by administering potentiated amoxycillin for 19 days, followed by a second treatment for 30 days should the disease recur, using the lower end of the range of dose rates recommended. As potentiated amoxycillin has a time-dependent mode of action, the risk of recurrence may be reduced by using a higher dose rate to ensure that conjunctival levels of the drug are maintained above the minimum inhibitory concentrations for a longer period.
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