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Processing-in-memory (PIM) chips that integrate processor logic into memory devices offer a new opportunity for bridging the growing gap between processor and memory speeds, especially for applications with high memory-bandwidth requirements. The Data-IntensiVe Architecture (DIVA) system combines PIM memories with one or more external host processors and a PIM-to-PIM interconnect. DIVA increases memory bandwidth through two mechanisms: (1) performing selected computation in memory, reducing the quantity of data transferred across the processor-memory interface; and (2) providing communication mechanisms called parcels for moving both data and computation throughout memory, further bypassing the processor-memory bus. DIVA uniquely supports acceleration of important irregular applications, including sparse-matrix and pointer-based computations. In this paper, we focus on several aspects of DIVA designed to effectively support such computations at very high performance levels: (1) the memory model and parcel definitions; (2) the PIM-to-PIM interconnect; and, (3) requirements for the processor-to-memory interface. We demonstrate the potential of PIMbased architectures in accelerating the performance of three irregular computations, sparse conjugate gradient, a natural-join database operation and an object-oriented database query.

These findings suggest that measuring serum HE4 concentrations along with CA125 concentrations may provide higher accuracy for detecting ovarian cancer.

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