The aim of this study was the development
and characterization
of a new microemulsion composed of sweet orange (Citrus sinensis L.) essential oils (EOCs) and evaluate its antibacterial and larvicide
profiles. The optimal combination of EOCs, surfactant (Kolliphor EL),
and water was achieved using a ternary phase diagram. EOCs were obtained
from orange peel by steam-distillation and analyzed by gas chromatograph–mass
spectrometer (GC-MS). A total of 25 compounds were identified, among
which 90 wt % was d-limonene. In order to determine antimicrobial
activity of the formulation, minimum inhibitory concentration (MIC)
assay was done. d-Limonene, limonene 1,2-epoxide, and β-mircene
showed a high antibacterial activity. Cell viability studies were
performed in L929 murine fibroblast as a cellular line, using the
MTT assay. A cell viability of 118% for EOCs and 117.7% for microemulsion
after 72 h was recorded indicating no relevant cytotoxic effect. In vivo studies, based on a wax moth, Galleria mellonella (G. mellonella), larvae as a model system showed
100% of larvae mortality under the influence of the microemulsion
with EOCs, while a second efficiency rating of 45% for larvae mortality
was reached for pure EOCs. These tests confirm a strong larvicide
activity for the essential oil, characterized by the highest concentration
of limonene as the larvicide agent. The loading of EOCs into microemulsions
offered an improved approach for the delivery of this oil which retained
its bioactivity, as shown in vitro and in vivo.
Artigo recebido em 14/06/2021. Última versão recebida em 27/06/2021. Aprovado em 28/06/2021. Avaliado pelo sistema Triple Review: a) Desk Review pelo Editor-Chefe; e b) Double Blind Review (avaliação cega por dois avaliadores da área).
Rapid technological change and globalization have created new challenges when it comes to the protection and processing of personal data. In 2018, Brazil presented a new law that has the proposal to inform how personal data should be collected and treated, to guarantee the security and integrity of the data holder. The purpose of this paper is to emphasize the principles of the General Law on Personal Data Protection, informing real cases of leakage of personal data and thus obtaining an understanding of the importance of gains that meet the interests of Internet users on the subject and its benefits to the entire Brazilian society.
Os sistemas de armazenamento são essenciais para a produção agrícola, principalmente para as cadeias produtivas de grãos. Entretanto, é dependente dos agentes públicos e privados para sua viabilização e manutenção como serviço. O presente estudo tem como objetivo avaliar como estão sendo realizadas as armazenagens de grãos nas diferentes Regiões do Brasil em relação aos agentes econômicos gestores: Iniciativa Privada, Governo, Cooperativa e Economia Mista. A metodologia para esse estudo se vale da Análise de Redes Sociais que permite investigar as relações entre os produtos armazenados e os tipos de agente econômicos presentes em cada região. Os resultados apresentaram que os armazéns muitas vezes têm uma grande variação dos tipos de grãos armazenados e existe um papel predominante da Iniciativa Privada na gestão desses sistemas de armazenamento.
Este trabalho apresenta o projeto do Total Sky Imager no IFPE Campus Pesqueira e seu impacto nos programas de iniciação científica e tecnológica do instituto. O Total Sky Imager (TSI) é um equipamento que captura imagens do céu e, a partir de um banco de conhecimentos e rede neural artificial, estima a irradiância solar a curto prazo. O projeto proposto foi iniciado em 2017 e está em andamento. Com potencial de gerar quarenta e oito planos de trabalho distintos, o
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.