We describe the development of the Mental Health Inventory (MHI), a new 38item measure of psychological distress and well-being, developed for use in general populations. The MHI was fielded in four large samples having quite different characteristics (N = 5,089). One data set was used to explore the MHI's factor structure, and confirmatory factor analyses were used for cross-validation. Results support a hierarchical factor model composed of a general underlying psychological distress versus well-being factor; a higher order structure defined by two correlated factors-Psychological Distress and Well-Being; and five correlated lower order factors-Anxiety, Depression, Emotional Ties, General Positive Affect, and Loss of Behavioral Emotional Control. Summated rating scales produced high internalconsistency estimates and substantial stability over a 1-year interval. Our results provide strong psychometric support for a hierarchical model and scoring options ranging from five distinct constructs to reliance on one summary index. This tradeoff, which is between the unique information contained in the subscales versus the simplicity of a single score, should be evaluated further.A review of general population mentalhealth-survey instruments pointed out important trends in questionnaire content and conceptual issues that deserve empirical attention (Ware, Johnston, Davies-Avery, & Brook, 1979). Early instruments were very heterogeneous in content (Gurin, 1960;Langner, 1962;Macmillan, 1957). They included measures of physical and psychosomatic symptoms, functional status, other health problems or worries, and health habits, in addition to measures of more straightforward psychological constructs (e.g., symptoms of anxiety and depression). More recent instruments seem to focus almost exclusively on the more straightforward psychological constructs (Bradburn, 1969;Cleary, Goldberg, & Kessler, 1982;Dupuy, 1972). Whereas the more heterogeneous measures may be satisfactory for testing hypotheses about health status in general, they do not seem to do well in distinguishing changes in mental health from changes in physical health (Ware et al., 1979; Ware, Brook, Davies-Avery, et al., 1980b).Another characteristic of more recently developed mental health surveys is their focus Requests for reprints should be sent to