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Herein is proposed a concise algorithmic procedure for deriving a minimum l∞-norm solution of the system of consistent linear equations Ax=b, where A is a m×n matrix, b is given as a m×1 vector and x is a n×1 unknown vector. The proposed algorithm is developed based on the geometrical analysis of the characteristics of the minimum infinity-norm solution. The proposed algorithm is well-structured so that it may be implemented easily through simple linear algebraic manipulation. For the case of n>m, the basic idea of the method is extended to finding internally mapped vertices when a n dimensional polytope is transformed into m dimensional polytope through consistent linear mapping A. The proposed method is applied to the task velocity analysis for robot manipulators with joint velocity constraints.

Objectives. We aimed to summarize and critically evaluate the available evidence regarding the efficacy and safety of acupuncture for children with autism spectrum disorder (ASD). Methods. We searched 13 databases for studies published up to December 2016. Randomized controlled trials (RCTs) evaluating the efficacy of acupuncture for children with ASD were included. Outcome measures were the overall scores on scales evaluating the core symptoms of ASD and the scores for each symptom, such as social communication ability and skills, stereotypies, language ability, and cognitive function. Effect sizes were presented as mean differences (MD). Results. Twenty-seven RCTs with 1736 participants were included. Acupuncture complementary to behavioral and educational intervention significantly decreased the overall scores on the Childhood Autism Rating Scale (CARS) (MD −8.10, 95% CI −12.80 to −3.40) and the Autism Behavior Checklist (MD −8.92, 95% CI −11.29 to −6.54); however, it was unclear which of the ASD symptoms improved. Acupuncture as a monotherapy also reduced the overall CARS score. The reported adverse events were acceptable. Conclusions. This review suggests that acupuncture may be effective and safe for pediatric ASD. However, it is not conclusive due to the heterogeneity of the acupuncture treatment methods used in the studies.

With the large number of women diagnosed and treated for breast cancer each year, the importance of studying recurrence has become evident due to most deaths from breast cancer resulting from tumor recurrence following therapy. To mitigate this, cellular and molecular pathways used by residual disease prior to recurrence must be studied. An altered metabolism has long been considered a hallmark of cancer, and several recent studies have gone further to report metabolic dysfunction and alterations as key to understanding the underlying behavior of dormant and recurrent cancer cells. Our group has used two probes, 2-[N-(7-nitrobenz-2-oxa-1, 3-diaxol-4-yl) amino]-2-deoxyglucose (2-NBDG) and tetramethyl rhodamine ethyl ester (TMRE), to image glucose uptake and mitochondrial membrane potential, respectively, to report changes in metabolism between primary tumors, regression, residual disease, and after regrowth in genetically engineered mouse (GEM)-derived mammospheres. Imaging revealed unique metabolic phenotypes across the stages of tumor development. Although primary mammospheres overexpressing Her2 maintained increased glucose uptake ("Warburg effect"), after Her2 downregulation, during regression and residual disease, mammospheres appeared to switch to oxidative phosphorylation. Interestingly, in mammospheres where Her2 overexpression was turned back on to model recurrence, glucose uptake was lowest, indicating a potential change in substrate preference following the reactivation of Her2, reeliciting growth. Our findings highlight the importance of imaging metabolic adaptions to gain insight into the fundamental behaviors of residual and recurrent disease. Implications: This study demonstrates these functional fluorescent probes' ability to report metabolic adaptations during primary tumor growth, regression, residual disease, and regrowth in Her2 breast tumors.

Articles you may be interested inPersistent photoconductivity due to trapping of induced charges in Sn/ZnO thin film based UV photodetector Cadmium sulfide ͑CdS͒ thin films with n-type semiconductor characteristics were prepared at room temperature on glass substrates by radio-frequency magnetron sputtering for photoconductive-sensor applications. Films deposited at room temperature exhibit polycrystalline phases and show smooth surface morphologies. The deposition rate of the films decreases with increasing working pressure. The dark-and photoresistances in 400-nm-thick CdS films deposited at 6.7ϫ 10 −1 Pa and 80 W were approximately 1 ϫ 10 5 and 3 ϫ 10 4 ⍀ / sq, respectively. Lowering both the dark-and photoresistances lowers the sensitivity ͑R dark / R photo ͒ of the resistance.

In this paper we propose a set of techniques for a real-time motion capture of a human body. The proposed motion capture system is based on low cost accelerometers, and is capable of identifying the body configuration by extracting gravity-related terms from the sensor data. One sensor unit is composed of 3 accelerometers arranged orthogonally to each other, and is capable of identifying 2 rotating angles of joints with 2 degrees of freedom. A geometric fusion technique is applied to cope with the uncertainty of sensor data. A practical calibration technique is also proposed to handle errors in aligning the sensing axis to the coordination axis. In the case where motion acceleration is not negligible compared with gravity acceleration, a compensation technique to extract gravity acceleration from the sensor data is proposed. Experimental results not only for individual techniques but also for human motion capturing with graphics are included.

The purpose of this study was to find any association of the bovine growth hormone (bGH) gene with growth and carcass quality traits in Korean native cattle, Hanwoo. Genomic DNA was extracted from 21 Hanwoo individuals, and the 47 to 2,528 bp region of the bGH 2,856 bp (GenBank accession number M57764) including the promoter and the five exons was sequenced. A total of ten bGH SNPs were confirmed, including four (253 C>T, 303 C>T, 502 C>T, and 559 G>A) in the promoter, one (679 C>T) in exon 1, one (1,692 T>C) in intron 3, and four (2141 C>G, 2258 C>T, 2277 C>T, and 2291 A>C) in exon 5. The ten bGH SNPs were genotyped for a sample of 242 Hanwoo steers and association tests were performed to find any significant SNP that was correlated with growth and carcass quality. Of the SNPs, the 303 C>T SNP in the promoter region was significantly associated with 6-month-old weight, the 559 G>A SNP with longissimus dorsi muscle area, the 2141 C>G SNP in exon 5 with daily weight gain, and the 2258 C>T SNP with daily weight gain and carcass weight (p<0.05). The significant SNPs need to be verified in other Hanwoo populations before considering implementation of marker-assisted selection for genetic improvement of growth and carcass quality in Hanwoo.