Nursing managers should implement measures to improve nurses' knowledge and attitudes regarding major immobility complications to reduce the incidence of these complications in bedridden patients.

Background Being bedridden, which is a common clinical phenomenon, causes a series of complications related to immobilization. Effective management of immobility complications requires a reasonable allocation of nursing resources. Unit‐level evidence about the relationship between nursing resources and immobility complications is lacking. Objectives To gain insight into nursing resources in China and explore the relationship between nursing resources and the incidence of major immobility complications among bedridden patients. The major immobility complications included in our study were pressure ulcers, deep vein thrombosis, pneumonia and urinary tract infection. Design A nationwide, multicenter, cross‐sectional survey. Setting From November 2015 to June 2016, 18 hospitals (six tertiary and 12 secondary) from six provinces and cities in different geographic regions (eastern, southern, western, northern and central) in China participated in our study. Participant Intensive care units, internal medicine and surgery wards with high proportions of bedridden patients were chosen as investigation sites. Of the total of 23,637 available patients in the selected wards, 19,530 were recruited. Methods Data on nursing resources and ward characteristics were collected mainly by questionnaire. The incidence of major immobility complications among bedridden patients was measured by trained investigators. Data on patient characteristics were collected from the patient record system of each hospital. Multilevel regression analysis was used to estimate the impact of nursing resources on the incidence of major immobility complications, adjusting for patient and ward characteristics. Results The study included 23,637 patients in 213 wards, and 19,530 were recruited. The incidence of the four complications was 0.77% (pressure ulcers), 0.82% (deep vein thrombosis), 3.39% (pneumonia) and 0.86% (urinary tract infection), and the overall incidence of major immobility complications was 5.41%. The incidence of major immobility complications was higher in wards not attaining the target bed‐to‐nurse ratios than in those that met these criteria (β = 0.44, 95% confidence interval [CI]: 0.02–0.87; OR = 1.553, 95% CI: 1.002–2.387). The incidence of major immobility complications was negatively associated with the proportion of nurses with intermediate or senior job titles (β = −2.12, 95% CI: −3.78 to −0.45; OR = 0.120, 95% CI: 0.023–0.638). However, the incidence of major immobility complications was unexpectedly positively associated with the proportion of nurses with a bachelor's degree or higher (β = 1.06, 95% CI: 0.31–1.81; OR = 2.886, 95% CI: 1.363–6.110). Conclusions Sufficient nurse staffing and higher professional titles of nurses might contribute to reducing the incidence of major immobility complications. Nurse experience was not related to the incidence of major immobility complications. However, the association between nurse education level and the incidence of major immobility complications requires further investigation....

Background Immobility is common and associated with adverse outcomes in hospitalized patients, especially older people. However, the factors contributing to mortality in bedridden patients are not well known. This study aimed to estimate short-term mortality and analyze risk factors that affect the prognosis of bedridden patients. Methods This was a multicenter study in China involving 23,738 patients admitted to 25 hospitals between November 2015 and June 2016. All-cause mortality was recorded for 90 days after enrollment regardless of whether death occurred before or after discharge. Socio-demographic and clinical information was obtained from an electronic database. Univariate and multivariate Cox regression analysis was used to identify factors associated with mortality.

NMR spectroscopy in anisotropic media has emerged as a powerful technique for the structural elucidation of organic molecules. Its application requires weak alignment of the analytes by means of suitable...

The formation of lyotropic liquid crystals (LCs) in two-dimensional (2D) colloidal dispersions enables the production of mesoscopic/macroscopic ordered materials from nanoscale building blocks. In contrast to graphene oxide (GO) LCs, the practical applications of MXene LCs are less exploited. This study bridges the gap by utilizing a simple and versatile fabrication method to prepare Ti 3 C 2 T x MXene LC that can be applied as a background-free alignment medium for the residual dipolar coupling (RDC) measurement of organic molecules. Ti 3 C 2 T x LC displays the size-and concentration-dependent alignment degree. Ti 3 C 2 T x nanoflakes with an average size of around 600 nm can provide the quadrupolar 2 H splitting of 71 Hz at a concentration of 50 mg/mL and show excellent fluidity at such a high concentration. Compared with other alignment media, Ti 3 C 2 T x LC exhibits the features of no-background and narrow line broadening, which actualizes the acquirement of clean and highquality NMR spectra for the accurate RDC extraction. Notably, the alignment of LCs is determined to be maintainable in the redispersed solution after freeze-drying, providing the great convenience for the preparation of alignment Ti 3 C 2 T x media, long-term sample preservation, and quantitative evaluation of alignment degree. Meanwhile, the alignment LC media for RDC measurement can be established in other MXenes such as Ti 2 CT x and Ti 3 CNT x . Collectively, our findings demonstrate the potential of creating various alignment media from the fascinating MXene family. KEYWORDS: Ti 3 C 2 T x , MXene, liquid crystal, alignment media, residual dipolar couplings (RDCs)

The subtle balance of the metrics of the highly supple 5,5′-pyridyl-3,3′-bis-1H-pyrazolate and the variable coordination numbers of Cu(I) favor the stabilization of a [4 × 4] grid complex with all Cu(I). It has numerous cuprophilic bonds (Cu•••Cu = 2.56−3.02 Å), and consequently, exhibits strong orange luminescence that fades upon insertion of solvents without loss of crystallinity.

Controlled hydration leads to four derivatives of a metal–organic framework consisting of cadmium ions, N 1,N 1,N 4,N 4-tetrakis­(4-(pyridin-4-yl)­phenyl)­benzene-1,4-diamine, and coordinated and free nitrates. The balance of water coordination and the multitude of bonding of the weakly coordinated nitrate lead to a progressive change in the coordination number of the Cd2+ ions from eight to seven to six without great perturbation to the 4-fold interpenetration three-dimensional framework.

Residual Dipolar Couplings (RDCs), acquired relying on weakly alignment media, are highly valuable for the structural elucidation of organic molecules. Arising from the striking features of no background signal and...