The sharp increase, out of proportion to other poison center calls, suggests a rising problem with teen ADHD stimulant medication abuse. Case severity increased over time. Sales data of ADHD medications suggest that the use and call-volume increase reflects availability, but the increase disproportionately involves amphetamines.
These results are close suggesting that the actual number is near these numbers. The NPDS number is greater than NEISS-AIP point estimate but within the 95% confidence interval. As NPDS is an actual count and NEISS-AIP is an extrapolation from a sample, to the extent that every child presenting to an ED following a medication exposure is not reported to a poison center, both databases may underestimate the problem. The NEISS-AIP extrapolation tool may need to be reassessed.
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