Objectives : The aim of this study is to examine the effect of external application containing herbal extracts (Betula platyphyllae Cortex, Viticis Fructus, Agrimoniae herba) to patients with atopic dermatitis.Methods : Twenty patients (experiment group) were treated with the external application containing herbal extracts (Betula platyphyllae Cortex, Viticis Fructus, Agrimoniae herba) and other twenty patients (control group) were treated with normal external application that doesn't contain herbal extracts for 2weeks. We observed comparisons between experiment and control group after 1week, 2weeks. Degrees of severity of atopic dermatitis were measured by SCORAD index (Scoring of Atopic Dermatitis Index). Statistical significance was achieved if the probability was less than 5% (p<0.05).Results : 1. After 1week of external application treatment, SCORAD Index in experiment group was significantly decreased comparing with control group , which is a marginally significant result between two groups. But after 2weeks the experiment group showed no statistically significant result. 2. After 1week of external application treatment, Intensity Criteria (Erythema, Edema/papulation, Total) in experiment group was significantly decreased comparing with control group, which is a statistically significant result between two groups. But after 2weeks the experiment group showed no statistically significant result.
Objectives : YangHyulEum Gami-Bang(YHEG) is a hair care extracts which is composed of fourteen plant extracts used in oriental medicine. The purpose of this study is to investigate the effect of YangHyulEum Gami-Bang(YHEG) on the alopecia and hair growth.Methods & Results : The herbal extracts from YangHyulEum Gami-Bang(YHEG) was tested using in vivo and in vitro test models.1. The YHEG extracts showed effect on the DNA proliferation of the hair dermal papilla cells measured by [3H]thymidine incorporation. 2. YHEG showed promoting on the expression of growth factors such as IGF-1, KGF-1 and inhibiting on the expression of inhibitory hair growth factor such as TGF-β1, BMP-2 estimated by qPCR. 3. The YHEG extracts showed effect on the activation of β-catenin in the dermal papilla cells. 4. YHEG showed inhibitory effects of NO synthesis at 0.2% concentrations. 5. YHEG showed effects in the expression of IL-1β, TNF-α, IL-6, COX-2 and iNOS gene in the LPS stimulated RAW 264.7 cells. 6. The hair growth index of the YHEG extracts ranked at over 2 when compared to control group which was ranked at 0. 7. The hair follicle number, length and size of the experimental group were remarkably higher than the control group in the histological observation. Conclusions : These results suggest that YangHyulEum Gami-Bang(YHEG) has hair growth promoting activity and it can be used as a potent treatment agent for preventing hair loss and stimulating hair growth for treatment of alopecia.
Objectives : The purpose of this study is to report the oriental treatment on Irritant Dermatitis Caused by Wood Vinegar on Pustulosis Palmaris et Plantaris.Methods : After using Wood Vinegar, a patient suffers from erythema, pruritus, pain, desquamation of skin and degeneration of Pustulosis Palmaris et Plantaris. The patient was admitted to Dunsan oriental hospital for 15 days and took an oriental(venesection, herbal-medicine, and vapor treatment) treatment. To evaluate the results of this treatment, the improvement of symptoms(vesicles, pruritus, pain) was identified by patient's subjective expression and in lesion-symptom improvement.Results : The symptoms caused by Wood vinegar on both palms and soles were improved but the desquamation of skin remained.Conclusions : This study shows that the oriental medical treatment effects on the irritant dermatitis caused by Wood Vinegar. Also, the public should be aware of indiscreetly-used, natural herbal products as a folk remedy.
Objectives : The purpose of this study is to report the oriental medical treatment on erythema multiforme caused by acute tonsillitis Methods : Patient who has been ill Acute tonsillitis suffers from erythema, edema, pruritus, burning sensation of systemic skin. The patient was admitted to Dunsan oriental hospital for 7 days and was treated with oriental medicine(acupuncture, herbal-medicine, and vapor treatment). To evaluate the results of this treatment, the improvement of symptoms(erythema, pruritus, burning sensation) was identified by patient's subjective expression and in lesion-symptom improvement.Results : The symptoms caused by acute tonsillitis on total skin were improved. Conclusions : This study shows that the oriental medical treatment effects on the erythema multiforme caused by acute tonsillitis. Also, the public suggests that the correlation between the skin and tonsil.
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