Vitamin B6 intake and 4-pyridoxic acid excretions of 22 children were determined. Mean intake of vitamin B6 per day was 1.10 mg +/- 0.47. Mean percentage of vitamin B6 intake excreted as 4-pyridoxic acid was 48% +/- 23. Excretion of 4-pyridoxic acid was significantly correlated to vitamin B6 intake but not to vitamin B6/protein ratios or vitamin B6/kilocalorie levels. Excretions of 4-pyridoxic acid equal to or below 0.15 mg appeared to be indicative of poor vitamin B6 intake for the children which was similar to the excretions found by others for depleted adults.
Creatinine per minute excretion rates in individual voidings varied as much as 300-500 percent of the 24-hour value for several children. Creatinine excretion rates were significantly more variable for children treated with anticonvulsant drugs than for normal children. Riboflavin-creatinine ratios determined on individual voidings were variable but adequate although total riboflavin was low. No time of day was found when creatinine excretion was representative of the 24-hour value. The creatinine height index when calculated from timed individual voidings during a 24-hour period varied for some children from 0.5 to more than 1.5 times published norms.
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