Urinary Riboflavin and Creatinine Excretion in Children Treated With Anticonvulsant Drugs

Fasting and Post-Methionine Loading Concentrations of Homocysteine, Vitamin B2, and Vitamin B6 in Patients on Antiepileptic Drugs

“…The recycling of folate cofactors is dependent on vitamin B 6 and B 2 , and vitamin B 2 is necessary for activating vitamin B 6 to pyridoxal 5Ј-phosphate (PLP) (9 ). Vitamin B 2 and B 6 status thus may have an impact on tHcy concentrations in patients taking AEDs, but few studies have reported on this matter (3,4,10,11 ). The methionine loading test detects individuals with impaired homocysteine metabolism not detected by fasting Hcy concentrations alone and is often considered primarily a test of the transsulfuration pathway (1,8,12 ).…”